Evidence map›Paper›PMID 29479479›Full record

ArticleVirus evolution2018

Mosquito bottlenecks alter viral mutant swarm in a tissue and time-dependent manner with contraction and expansion of variant positions and diversity.

Edward I Patterson, Kamil Khanipov, Mark M Rojas, Tiffany F Kautz, Dedeke Rockx-Brouwer, Georgiy Golovko, Levent Albayrak, Yuriy Fofanov, Naomi L Forrester

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  9. A Review:Pathogens (Basel, Switzerland) · 2020
    Review
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  14. Review
  15. Review
  16. Mapping Arbovirus-Vector Interactions Using Systems Biology Techniques.Frontiers in cellular and infection microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Edward I PattersonDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0610, USA.ORCID 0000-0003-3465-0848
Kamil KhanipovDepartment of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555-0617, USA.
Mark M RojasDepartment of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555-0617, USA.
Tiffany F KautzDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0610, USA.
Dedeke Rockx-BrouwerDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0610, USA.
Georgiy GolovkoDepartment of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555-0617, USA.
Levent AlbayrakDepartment of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555-0617, USA.
Yuriy FofanovDepartment of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555-0617, USA.
Naomi L ForresterDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0610, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Effects of Arboviral Population Diversity on TransmissionR01AI095753 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI THANGAMANI, SARAVANAN · 2014 to 2018
$1.9M
NIAID NIH HHS R01 AI095753
6 · The paper itself

Abstract

Viral diversity is theorized to play a significant role during virus infections, particularly for arthropod-borne viruses (arboviruses) that must infect both vertebrate and invertebrate hosts. To determine how viral diversity influences mosquito infection and dissemination

Indexed as

arbovirusbottlenecksminority variantsquasispeciesvirus diversity

Identifiers

PMID29479479
PMCPMC5814806
OpenAlexW2793924325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.