Evidence map›Paper›PMID 29479477›Full record

ArticleNPJ genomic medicine2018

Clinical testing of

Amanda Ewart Toland, Andrea Forman, Fergus J Couch, Julie O Culver, Diana M Eccles, William D Foulkes, Frans B L Hogervorst, Claude Houdayer, Ephrat Levy-Lahad, Alvaro N Monteiro and 7 more

Open access · goldAbstract read
In one paragraph

Article in NPJ genomic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Contemporary risk assessment and risk-reducing strategies for tubo-ovarian cancer in women with BRCA pathogenic variants.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Assessment ofJCO clinical cancer informatics · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Targeting theFrontiers in cell and developmental biology · 2023
    Review
  14. Article
  15. Article
  16. Cell-type-specific epigenomic variations associated withNAR genomics and bioinformatics · 2022
    Article
  17. Article
  18. BRCA1 and Breast Cancer: Molecular Mechanisms and Therapeutic Strategies.Frontiers in cell and developmental biology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 7 countries.

Amanda Ewart Toland1Departments of Cancer Biology and Genetics and Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210 USA.ORCID 0000-0002-0271-1792
Andrea Forman2Fox Chase Cancer Center, Philadelphia, PA 19111 USA.
Fergus J Couch3Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905 USA.
Julie O Culver4USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033 USA.
Diana M Eccles5Faculty of Medicine, University of Southampton, Southampton, S016 5YA UK.
William D Foulkes6Departments of Human Genetics, Medicine and Oncology, McGill University, Montreal, QC Canada H4A 3J1.ORCID 0000-0001-7427-4651
Frans B L Hogervorst7Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, 1006 BE Netherlands.
Claude Houdayer8Oncogenetics and INSERM U830, Institut Curie, Paris and Paris Descartes University, Paris, 75248 France.
Ephrat Levy-Lahad9Faculty of Medicine, Shaare Zedek Medical Center, Hebrew University of Jerusalem and Medical Genetics Institute, Jerusalem, 9103102 Israel.
Alvaro N Monteiro10Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612 USA.ORCID 0000-0002-8448-4801
Susan L Neuhausen11Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA 91010 USA.
Sharon E Plon12Baylor College of Medicine, Houston, TX 77030 USA.
Shyam K Sharan13Mouse Cancer Genetics Program, Center for Cancer Biology, National Cancer Institute, National Institutes of Health, Frederick, MD 21702-1201 USA.
Amanda B Spurdle14Genetics and Computational Biology Division, QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD QLD 4006 Australia.
Csilla Szabo15National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Lawrence C Brody15National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 USA.
BIC Steering Committee
National Institutes of Health · USBaylor College of Medicine · USCancer Genetics (United States) · USCity of Hope · USDélégation Paris 5 · FRFox Chase Cancer Center · USHebrew University of Jerusalem · ILMayo Clinic · USMcGill University · CAMoffitt Cancer Center · USQIMR Berghofer Medical Research Institute · AUThe Netherlands Cancer Institute · NLUniversity of Southampton · GBUniversity of Southern California · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Functional Analysis of Variants Identified in Human Breast Cancer SusceptibilityZIABC011181 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SHARAN, SHYAM · 2009 to 2025
$11.6M
The role of the BRCA1 and BRCA2 gene in the pathogenesis of breast cancerZIAHG000120 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BRODY, LAWRENCE C · 2009 to 2019
$980k
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

Clinical testing of

Identifiers

PMID29479477
PMCPMC5814433
OpenAlexW2802269419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.