Evidence map›Paper›PMID 29479470›Full record

ArticleNPJ biofilms and microbiomes2018

Tools for studying growth patterns and chemical dynamics of aggregated

Majken Sønderholm, Klaus Koren, Daniel Wangpraseurt, Peter Østrup Jensen, Mette Kolpen, Kasper Nørskov Kragh, Thomas Bjarnsholt, Michael Kühl

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The non-attached biofilm aggregate.Communications biology · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Improve Integration of In Vitro Biofilm Body of Knowledge to Support Clinical Breakthroughs in Surgical Site Infection.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Tolerance and Resistance ofFrontiers in microbiology · 2019
    Review
  18. Oxygen Restriction Generates Difficult-to-CultureFrontiers in microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Majken Sønderholm1Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.ORCID 0000-0001-9576-5775
Klaus Koren2Marine Biology Section, Department of Biology, University of Copenhagen, Strandpromenaden 5, DK-3000 Helsingør, Denmark.ORCID 0000-0002-7537-3114
Daniel Wangpraseurt2Marine Biology Section, Department of Biology, University of Copenhagen, Strandpromenaden 5, DK-3000 Helsingør, Denmark.
Peter Østrup Jensen1Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.
Mette Kolpen4Department of Clinical Microbiology 9301, Copenhagen University Hospital, Rigshospitalet, Juliane Maries Vej 22, Copenhagen, Denmark.ORCID 0000-0001-5575-0384
Kasper Nørskov Kragh1Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.
Thomas Bjarnsholt1Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.ORCID 0000-0002-8003-7414
Michael Kühl2Marine Biology Section, Department of Biology, University of Copenhagen, Strandpromenaden 5, DK-3000 Helsingør, Denmark.ORCID 0000-0002-1792-4790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In chronic infections, bacterial pathogens typically grow as small dense cell aggregates embedded in a matrix consisting of, e.g., wound bed sludge or lung mucus. Such biofilm growth mode exhibits extreme tolerance towards antibiotics and the immune defence system. The bacterial aggregates are exposed to physiological heterogeneity and O

Identifiers

PMID29479470
PMCPMC5818519

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.