ArticleGastroenterology report2018
Ulcerative Colitis Endoscopic Index of Severity (UCEIS) versus Mayo Endoscopic Score (MES) in guiding the need for colectomy in patients with acute severe colitis.
Article in Gastroenterology report, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Predictors for colectomy in patients with acute severe ulcerative colitis: a systematic review and meta-analysis.BMJ open gastroenterology · 2024Pooled it
- Real-World Efficacy and Safety Monitoring for Predicting Continuation of Tofacitinib Therapy in Patients with Ulcerative Colitis.Digestive diseases and sciences · 2022Trial
- Validation of the immune-mediated colitis endoscopic score using a retrospective cohort of patients with immune-mediated colitis.iGIE : innovation, investigation and insights · 2026Article
- Beyond conventional endoscopy: Image-enhanced techniques in quiescent ulcerative colitis assessment.World journal of gastrointestinal endoscopy · 2026Review
- Progressive Disease Image Generation with Ordinal-Aware Diffusion Models.Diagnostics (Basel, Switzerland) · 2025Article
- Relationship of Intestinal Ultrasound With Clinical, Biochemical, and Endoscopic Disease Severity in Acute Severe Ulcerative Colitis: A Blinded, Prospective Study.Clinical and translational gastroenterology · 2025Article
- Seroprevalence of CMV infection in patients with active ulcerative colitis and underlying factors of pathogenicity.BMC infectious diseases · 2025Article
- Comparison of Fecal Calprotectin and Myeloperoxidase in Predicting Outcomes in Inflammatory Bowel Disease.Inflammatory bowel diseases · 2025Article
- Optimizing 5-aminosalicylate for moderate ulcerative colitis: expert recommendations from the Asia-Pacific, Middle East, and Africa Inflammatory Bowel Disease Coalition.Intestinal research · 2025Review
- The Disease Severity Index for Inflammatory Bowel Disease Is a Valid Instrument that Predicts Complicated Disease.Inflammatory bowel diseases · 2024Article
- Management of Severe Colitis and Toxic Megacolon.Clinics in colon and rectal surgery · 2024Review
- Development and investigation of a non-invasive disease severity index for inflammatory bowel disease.Journal of Crohn's & colitis · 2024Article
- Clinical Utility of Disease Activity Indices in Predicting Short-Term Response to Biologics in Patients with Ulcerative Colitis.Journal of clinical medicine · 2024Article
- Artificial Intelligence and IBD: Where are We Now and Where Will We Be in the Future?Current gastroenterology reports · 2024Review
- Managing Ulcerative Colitis and Crohn's Disease: Should the Target Be Endoscopy, Histology, or Both?Journal of the Canadian Association of Gastroenterology · 2024Article
- Comparison of fecal calprotectin levels and endoscopic scores for predicting relapse in patients with ulcerative colitis in remission.World journal of gastroenterology · 2023Article
- [Value of Improved Mayo Endoscopic Score for evaluating treatment efficacy for active ulcerative colitis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Real-life effectiveness and safety of tofacitinib treatment in patients with ulcerative colitis: a KASID multicenter cohort study.Therapeutic advances in gastroenterology · 2023Article
- Faecal Myeloperoxidase as a Biomarker of Endoscopic Activity in Inflammatory Bowel Disease.Journal of Crohn's & colitis · 2022Article
- Expression of CD44 in Leukocyte Subpopulations in Patients with Inflammatory Bowel Diseases.Diagnostics (Basel, Switzerland) · 2022Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and the Mayo Endoscopic Score (MES) were developed as an objective method of the endoscopic severity in ulcerative colitis (UC); however, it was still unclear whether UCEIS
methodsConsecutive ASC patients between January 2012 and May 2016 were retrospectively evaluated. Demographic data, previous therapy, clinical observations, laboratory parameters, medical therapy and endoscopic assessments were documented. The primary outcome was the need for colectomy during admission and follow-up.
resultsNinety-two patients were enrolled. 37 (40.2%) needed colectomy. UCEIS score is a predictor of requirement for colectomy in multivariate analysis (OR, 3.25; 95% CI, 1.77-5.97; P < 0.001). Receiver-operator characteristic (ROC) area of UCEIS is 0.85, with a sensitivity of 60.3% and specificity of 85.5% using cut-off value of 7, which outperforms MES with the ROC area of 0.65; When UCEIS score ≥7, 80% of patients eventually need colectomy.
conclusionUCEIS outperformed MES as a predictor for need for colectomy in ASC patients. The high probability of medical treatment failure and benefits of early colectomy should be discussed in patients with baseline UCEIS ≥ 7.Acute severe colitis; colectomy; Ulcerative Colitis Endoscopic Index of Severity; Mayo Endoscopic Score.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.