ReviewGastroenterology report2018
Interventions to improve physical function and prevent adverse events in cirrhosis.
Review in Gastroenterology report, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Controversies in Diagnosing Sarcopenia in Cirrhosis-Moving from Research to Clinical Practice.Nutrients · 2019Pooled it
- Effect of non-alcoholic beer, diet and exercise on endothelial function, nutrition and quality of life in patients with cirrhosis.World journal of hepatology · 2020Trial
- Strength training intervention with creatine/whey protein supplementation vs placebo on frailty in older adults with cirrhosis (STRIVE): A Randomized Controlled Trial.Research square · 2026Article
- Wearable Sensors and Artificial Intelligence for Ecological Knee Osteoarthritis Assessment: Development and Feasibility of a Hybrid Digital Phenotyping Framework.Sensors (Basel, Switzerland) · 2026Article
- Relationship Between Cognitive Function and Balance, Fatigue, and Physical Activity Levels in Patients with Liver Cirrhosis.Healthcare (Basel, Switzerland) · 2026Article
- Article
- The Role of Exercise in Steatotic Liver Diseases: An Updated Perspective.Liver international : official journal of the International Association for the Study of the Liver · 2025Review
- Falls and malnutrition are associated with in-hospital mortality in patients with cirrhosis.Hepatology communications · 2024Article
- Walking exercise through smartphone application plus branched-chain amino acid supplementation benefits skeletal muscle mass and strength in liver cirrhosis: A prospective control trial.Zeitschrift fur Gastroenterologie · 2024Article
- Frequentmers - a novel way to look at metagenomic next generation sequencing data and an application in detecting liver cirrhosis.BMC genomics · 2023Article
- Identifying opportunities for hepatic encephalopathy self-management: A mixed methods systematic review and synthesis.Canadian liver journal · 2023Article
- Effects of an active lifestyle on the physical frailty of liver transplant candidates.World journal of transplantation · 2022Article
- Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease.Croatian medical journal · 2021Observational
- Article
- Neurocognitive and Muscular Capacities Are Associated with Frailty in Adults with Cirrhosis.Digestive diseases and sciences · 2020Article
- Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy.Journal of clinical medicine · 2020Article
- Patients with Alcoholic Liver Disease Have Worse Functional Status at Time of Liver Transplant Registration and Greater Waitlist and Post-transplant Mortality Which Is Compounded by Older Age.Digestive diseases and sciences · 2020Article
- Osteoporosis in Primary Biliary Cholangitis: Prevalence, Impact and Management Challenges.Clinical and experimental gastroenterology · 2020Review
- Frailty, Psychoactive Medications, and Cognitive Dysfunction Are Associated With Poor Patient-Reported Outcomes in Cirrhosis.Hepatology (Baltimore, Md.) · 2019Article
- Design and rationale of a randomized-controlled trial of home-delivered meals for the management of symptomatic ascites: the SALTYFOOD trial.Gastroenterology report · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Cirrhosis is associated with debilitating complications that significantly impact on a patient's physical function and reduce quality of life. Owing to highly prevalent sarcopenia, malnutrition and hepatic encephalopathy, functional impairment or frailty is a common complication of cirrhosis. Frailty in turn increases the patient's risk of hospitalization, accidental falls and fractures, and death. The management of frailty and its associated adverse effects is imperative in improving the overall prognosis of patients with advanced liver disease. The cornerstone of therapy revolves around optimizing physical function with appropriate nutrition and exercise. Nutritional therapy with protein supplementation has shown significant benefit, while studies on exercise have been controversial. However, newly emerging studies trend towards a beneficial effect of physical exercise with improvement in quality of life. The implementation of technology in liver disease management shows future promise. Fitbits and other wearable devices can be used to help monitor a patient's personal progress in physical exercise and nutritional optimization. Additionally, the progressive development of new smartphone applications to help aid in the diagnosis and monitoring of complications of cirrhosis provides a sophisticated avenue for improving care of patients with cirrhosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.