Evidence map›Paper›PMID 29479396›Full record

ArticleJournal of extracellular vesicles2017

Characterization of extracellular vesicles derived from cardiac cells in an

Sebastian Borosch, Eva Dahmen, Christian Beckers, Christian Stoppe, Eva Miriam Buhl, Bernd Denecke, Andreas Goetzenich, Sandra Kraemer

Abstract read
In one paragraph

Article in Journal of extracellular vesicles, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Noncoding RNAs regulating cardiac muscle mass.Journal of applied physiology (Bethesda, Md. : 1985) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastian BoroschDepartment of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Eva DahmenDepartment of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Christian BeckersDepartment of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Christian StoppeCardiovascular Critical Care & Anesthesia research and evaluation (3CARE), University Hospital RWTH Aachen, Aachen, Germany.ORCID 0000-0002-2028-2039
Eva Miriam BuhlElectron Microscopy Facility, University Hospital RWTH Aachen, Aachen, Germany.ORCID 0000-0003-0627-9228
Bernd DeneckeInterdisciplinary Center for Clinical Research, University Hospital RWTH Aachen, Aachen, Germany.
Andreas GoetzenichDepartment of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Sandra KraemerDepartment of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preconditioning is a promising technique to protect the heart from ischaemia-reperfusion injury. In this context, the crosstalk between different cardiac cell types and especially the exchange of cardioprotective mediators has come into the focus of current research. Recently, extracellular vesicles (EVs), nano-sized structures, emerged as possible communication mediators. They are taken up by recipient cells and can alter gene expression or activate intracellular signal cascades. It has been shown that all cardiac cell types are able to secrete EVs, but so far the influence of an

Indexed as

cardiac cellscardioprotectionExtracellular vesiclesin vitro preconditioningmiRNAvolatile anaesthetics

Identifiers

PMID29479396
PMCPMC5819478

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.