ArticleFrontiers in endocrinology2018
The Natural History of Metabolic Comorbidities in Turner Syndrome from Childhood to Early Adulthood: Comparison between 45,X Monosomy and Other Karyotypes.
Article in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Clinical practice guidelines for the care of girls and women with Turner syndrome.European journal of endocrinology · 2024Guideline
- Cytomolecular Analysis of a Ring X Chromosome in a Patient with Turner Syndrome: A Case Report.Molecular syndromology · 2026Article
- Management of Childhood Obesity.International journal of molecular sciences · 2026Review
- Adipose tissue distribution and metabolic profile of young individuals with turner syndrome.Journal of the Endocrine Society · 2026Article
- Inherited aortopathies and risk of aortic dissection and aortic syndrome in pregnancy.Obstetric medicine · 2026Review
- Cardiovascular phenotypes of children and adolescents with Turner syndrome from a single-center cohort study.Orphanet journal of rare diseases · 2025Article
- Isogenic hiPSC models of Turner syndrome development reveal shared roles of inactive X and Y in the human cranial neural crest network.American journal of human genetics · 2025Article
- Metabolic Risk in Patients with a Diminished Ovarian Reserve and Premature Ovarian Insufficiency.Journal of clinical medicine · 2024Article
- Are Young People with Turner Syndrome Who Have Undergone Treatment with Growth and Sex Hormones at Higher Risk of Metabolic Syndrome and Its Complications?Biomedicines · 2024Article
- Isogenic hiPSC models of Turner syndrome development reveal shared roles of inactive X and Y in the human cranial neural crest network.bioRxiv : the preprint server for biology · 2024Article
- A single-center's uric acid profile in girls with Turner syndrome.Frontiers in endocrinology · 2024Observational
- Article
- Breast satisfaction in adult women with Turner syndrome-An international survey employing the BREAST-Q questionnaire.Clinical endocrinology · 2023Article
- Hyperglycemia in Turner syndrome: Impact, mechanisms, and areas for future research.Frontiers in endocrinology · 2023Review
- Turner syndrome: French National Diagnosis and Care Protocol (NDCP; National Diagnosis and Care Protocol).Orphanet journal of rare diseases · 2022Article
- Does the Value of FSH Predict Severity of Metabolic Complications in Females with POI?Journal of clinical medicine · 2022Article
- Genetic conditions of short stature: A review of three classic examples.Frontiers in endocrinology · 2022Review
- The Cutoff of Gonadotropins for Close Evaluation of Cardiometabolic Risk Factors in Turner Syndrome.International journal of preventive medicine · 2022Article
- Epicardial and Perihepatic Fat as Cardiometabolic Risk Predictors in Girls with Turner Syndrome: A Cardiac Magnetic Resonance StudyJournal of clinical research in pediatric endocrinology · 2021Article
- Genetic Investigation of 261 Cases of Turner Syndrome Patients Referred to the Genetic Clinic.Iranian journal of public health · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatients with Turner syndrome (TS) are at increased risk for metabolic disorders. We aimed to delineate the occurrence and evolution of metabolic comorbidities in TS patients and to determine whether these differ in 45,X monosomy and other karyotypes.
methodsA longitudinal and cross-sectional retrospective cohort study was conducted in a tertiary pediatric endocrine unit during 1980-2016. Ninety-eight TS patients, 30 with 45,X monosomy were followed from childhood to early adulthood. Outcome measures included weight status, blood pressure (BP), glucose metabolism, and lipid profile.
resultsLongitudinal analysis showed a significant change in body mass index (BMI) percentiles over time [
conclusionOur longitudinal study provides unique insights into the evolution of weight gain and metabolic disorders from childhood to early adulthood in TS patients. Since overweight and increasing age aggravate the risk for metabolic comorbidities, careful surveillance is warranted to prevent and control obesity already from childhood. The more prominent clustering of metabolic comorbidities in 45,X monosomy underscores the importance of a more vigorous intervention in this group.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.