Evidence map›Paper›PMID 29479301›Full record

ArticleFrontiers in neuroscience2018

Homer1a Attenuates Hydrogen Peroxide-Induced Oxidative Damage in HT-22 Cells through AMPK-Dependent Autophagy.

Xiuquan Wu, Peng Luo, Wei Rao, Shuhui Dai, Lei Zhang, Wenke Ma, Jingnan Pu, Yang Yu, Jiu Wang, Zhou Fei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Parkin protects against traumatic brain injury through regulating mitochondrial quality control.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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  6. Review
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  8. Review
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  10. Article
  11. STING-Mediated Autophagy Is Protective against HInternational journal of molecular sciences · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiuquan WuDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Peng LuoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wei RaoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Shuhui DaiDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Lei ZhangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wenke MaDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jingnan PuDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yang YuDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jiu WangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhou FeiDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xijing Hospital · CNAir Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal oxidative stress is involved in diverse neurological disorders. Homer1a, as an important member of the Homer family and localized at the postsynaptic density, is known to protect cells against oxidative injury. However, the exact neuroprotective mechanism of Homer1a has not been fully elucidated. Here, we found that Homer1a promoted cell viability and reduced H

Indexed as

AMPKautophagyHomer1ahydrogen peroxidemitochondrial dysfunctionoxidative stress

Identifiers

PMID29479301
PMCPMC5811507
OpenAlexW2786065438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.