Evidence map›Paper›PMID 29479212›Full record

ArticlePaediatrics & child health2017

Physician and parent barriers to the use of oral corticosteroids for the prevention of paediatric URTI-induced acute asthma exacerbations at home.

Neale Smith, Anne Smith, Alice Wang, Kaitlyn Shaw, Gabriella Groeneweg, Ran D Goldman, Bryan Wilkinson, Ricardo Jimenez, Leah Mwai, Bruce Carleton

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Paediatrics & child health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Short-course systemic corticosteroids in asthma: striking the balance between efficacy and safety.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Neale SmithCentre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, British Columbia.
Anne SmithDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Alice WangFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia.
Kaitlyn ShawDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Gabriella GroenewegDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Ran D GoldmanDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Bryan WilkinsonDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Ricardo JimenezDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Leah MwaiDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Bruce CarletonDivision of Translational Therapeutics, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
University of British Columbia · CAChild and Family Research Institute · CATranslational Therapeutics (United States) · USBC Children's Hospital · CAFamily Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAdministration of oral corticosteroids at the onset of an upper respiratory tract infection (URTI) can be effective in the management of acute asthma exacerbations in children. This study was designed to identify barriers to parent-initiated implementation of clinical practice guideline-recommended use of oral corticosteroids for prophylaxis against severe asthma exacerbations in children.

methodsTwenty-seven children who presented to BC Children's Hospital with URTI-induced asthma exacerbations were recruited. Parents received a filled prescription for a course of oral corticosteroids to be used at the earliest onset of their child's next URTI. Each family was contacted monthly over a 1-year period to inquire about URTI events, asthma symptoms, medication use and health care utilization. Focus groups were held with family physicians, paediatricians and parents; transcripts were analyzed qualitatively to identify key themes.

resultsIncidence of URTI events among participants was high (85%). Uptake of study medication was low; 44% used the medication as directed at their first URTI event. Eleven per cent of the patients who used the study medication also visited the emergency department for an exacerbation. Focus groups identified four main barriers to the effective use of parent-initiated oral corticosteroids: physician resistance and conflicting messages from providers; parent uncertainty about oral corticosteroids; multiple caregivers and relative ease of access to an emergency department.

conclusionWe have identified key barriers to the effective use of parent-administered oral corticosteroids as an asthma management strategy and gained important insights regarding the research that is required to enhance the applicability of the strategy.

Indexed as

Asthma exacerbation preventionOral corticosteroidsPaediatric asthma.

Identifiers

PMID29479212
PMCPMC5804881
OpenAlexW2610454459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.