Evidence map›Paper›PMID 29479053›Full record

ArticleHigh-throughput2017

A Computational Workflow Translates a 58-Gene Signature to a Formalin-Fixed, Paraffin-Embedded Sample-Based Companion Diagnostic for Personalized Treatment of the BRAF-Mutation-Like Subtype of Colorectal Cancers.

Sjors G J G In 't Veld, Kim N Duong, Mireille Snel, Anke Witteveen, Inès J Beumer, Leonie J M J Delahaye, Diederik Wehkamp, René Bernards, Annuska M Glas, Sun Tian

Open access · goldAbstract read
In one paragraph

Article in High-throughput, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sjors G J G In 't VeldDepartment of Neurosurgery, VU University Medical Center, 1081HV Amsterdam, The Netherlands. g.intveld1@vumc.nl.
Kim N DuongAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. kim.duong@agendia.com.
Mireille SnelAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. mireille.snel@agendia.com.
Anke WitteveenAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. anke.witteveen@agendia.com.
Inès J BeumerAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. ines.beumer@agendia.com.
Leonie J M J DelahayeAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. leonie.delahaye@agendia.com.
Diederik WehkampAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. diederik.wehkamp@agendia.com.
René BernardsAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. r.bernards@nki.nl.
Annuska M GlasAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. annuska.glas@agendia.com.
Sun TianAgendia NV, Science Park 406, 1098XH Amsterdam, The Netherlands. sun.tian@agendia.com.
Agendia (Netherlands) · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLThe Netherlands Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer patients with the

Indexed as

bioinformatics workflowBRAF-mutation-like subtypecolorectal cancercompanion diagnosticdrug repurposingpersonalized medicine

Identifiers

PMID29479053
PMCPMC5748595
OpenAlexW2765226883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.