Evidence map›Paper›PMID 29479043›Full record

ArticleThe Journal of veterinary medical science2018

Sound exposure-induced cytokine gene transcript profile changes in captive bottlenose dolphin (Tursiops truncatus) blood identified by a probe-based qRT-PCR.

I-Hua Chen, Lien-Siang Chou, Shih-Jen Chou, Jiann-Hsiung Wang, Jeffrey Stott, Myra Blanchard, I-Fan Jen, Wei-Cheng Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Causes and consequences of intraspecific variation in animal responses to anthropogenic noise.Behavioral ecology : official journal of the International Society for Behavioral Ecology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

I-Hua ChenDepartment of Veterinary Medicine, National Chiayi University, No. 580, Xinmin Rd., Chiayi, Taiwan (R.O.C.).
Lien-Siang ChouInstitute of Ecology and Evolutionary Biology, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei, Taiwan (R.O.C.).
Shih-Jen ChouDepartment of Veterinary Medicine, National Chiayi University, No. 580, Xinmin Rd., Chiayi, Taiwan (R.O.C.).
Jiann-Hsiung WangDepartment of Veterinary Medicine, National Chiayi University, No. 580, Xinmin Rd., Chiayi, Taiwan (R.O.C.).
Jeffrey StottSchool of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, U.S.A.
Myra BlanchardSchool of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, U.S.A.
I-Fan JenFarglory Ocean Park, No.189, Yenliao Village, Shoufong, Hualien, Taiwan (R.O.C.).
Wei-Cheng YangDepartment of Veterinary Medicine, National Chiayi University, No. 580, Xinmin Rd., Chiayi, Taiwan (R.O.C.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cetacean health may be potentially affected by anthropogenic sound. We have initiated investigations on the effect of low-frequency underwater sound on immunological gene transcript profiles of captive bottlenose dolphins (Tursiops truncatus) using a probe-based quantitative gene expression assay. Six immunologic genes (IL-2Rα, -4, -10, -12, TNFα and IFNγ) were selected for analysis using two validated housekeeping genes (PGK1 and HPRT1) as reference genes. Twenty-four blood samples from six clinically healthy individuals and six blood samples from individuals after sound exposures were available. The gene transcript profile of sound-exposed dolphins was consistent with a stress-induced T

Indexed as

SoundAnimalsBottle-Nosed DolphinCytokinesGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionStress, PhysiologicalCytokinescytokinedolphinimmune responseqRT-PCRsound

Identifiers

PMID29479043
PMCPMC5938186

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.