Evidence map›Paper›PMID 29479016›Full record

ArticleIndustrial health2018

Asbestos exposure biomarkers in the follow-up of asbestos-exposed workers.

Valentina Paolucci, Riccardo Romeo, Antonietta Gerardina Sisinni, Giuseppina Scancarello, Luca Volterrani, Maria Antonietta Mazzei, Lucio Barabesi, Pietro Sartorelli

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Industrial health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Lung Cancer Imaging: Screening Result and Nodule Management.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Valentina PaolucciDepartment of Medical Biotechnology, University of Siena, Italy.
Riccardo RomeoUnit of Occupational Health, Azienda Ospedaliera Universitaria Senese, Italy.
Antonietta Gerardina SisinniUnit of Occupational Health, Azienda Ospedaliera Universitaria Senese, Italy.
Giuseppina ScancarelloUnit of Occupational Hygiene and Toxicology, Laboratory of Public Health AUSL South-East Tuscany, Italy.
Luca VolterraniDepartment of Medical Surgical and Neurological Science, University of Siena, Unit of Diagnostic Imaging Azienda Ospedaliera Universitaria Senese, Italy.
Maria Antonietta MazzeiDepartment of Medical Surgical and Neurological Science, University of Siena, Unit of Diagnostic Imaging Azienda Ospedaliera Universitaria Senese, Italy.
Lucio BarabesiDepartment of Economics and Statistics, University of Siena, Italy.
Pietro SartorelliDepartment of Medical Biotechnology, University of Siena, Unit of Occupational Health Azienda Ospedaliera Universitaria Senese, Italy.
Azienda Ospedaliera Universitaria Senese · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health surveillance of asbestos exposed workers should be stratified according to the exposure level. Unfortunately there is a lack of information regarding asbestos exposure in many working places and markers of asbestos exposure are often needed. The aim of the study was to assess the reliability of different dose and effect biomarkers in the follow up of asbestos-exposed workers. Mineralogical analysis of bronchoalveolar lavage fluid (BALF) as a biomarker of asbestos fibre burden was performed in a population of 307 male subjects occupationally exposed to asbestos. Using nonparametric statistical methods 8 variables were analyzed with respect to asbestos-related diseases and working sectors. The existence of a relationship between serum soluble mesothelin-related peptides (SMRP) and asbestos exposure levels was also investigated. Concentrations of amphiboles, chrysotile and asbestos bodies in BALF were higher in patients with asbestosis as well as in railway industry workers. A correlation between the onset of non malignant asbestos-related diseases and the levels of SMRP concentration was not found. This study confirms that fibre concentration in BALF may be considered as a reliable biomarker of previous asbestos exposure, whereas SMRP does not appear to be influenced by asbestos exposure levels.

Indexed as

Bronchoalveolar Lavage FluidAdultAgedAged, 80 and overAsbestosAsbestosisBiomarkersFollow-Up StudiesGPI-Linked ProteinsHumansItalyMaleMesothelinMiddle AgedOccupational ExposureRailroadsAsbestosBiomarkersGPI-Linked ProteinsMesothelinAmphiboleAsbestosAsbestosisBiomarkersBronchoalveolar lavageMesothelin

Identifiers

PMID29479016
PMCPMC5985464
OpenAlexW2793177380

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.