Evidence map›Paper›PMID 29478895›Full record

ArticleStem cell reports2018

High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells.

Steven M Garcia, Stanley Tamaki, Solomon Lee, Alvin Wong, Anthony Jose, Joanna Dreux, Gayle Kouklis, Hani Sbitany, Rahul Seth, P Daniel Knott and 6 more

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Asthma and stem cell therapy.World journal of stem cells · 2025
    Review
  3. Article
  4. Stem/progenitor cell-based therapy for Duchenne muscular dystrophy.Frontiers in cell and developmental biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Human Tissue-Engineered Skeletal Muscle: A Tool for Metabolic Research.Endocrinology and metabolism (Seoul, Korea) · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Steven M GarciaDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Stanley TamakiDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Solomon LeeDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Alvin WongDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Anthony JoseDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Joanna DreuxDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Gayle KouklisDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Hani SbitanyDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Rahul SethDepartment of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
P Daniel KnottDepartment of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
Chase HeatonDepartment of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
William R RyanDepartment of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
Esther A KimDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Scott L HansenDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
William Y HoffmanDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of California, San Francisco, CA 94143, USA.
Jason H PomerantzDepartments of Surgery and Orofacial Sciences, Division of Plastic and Reconstructive Surgery, Program in Craniofacial Biology, Eli and Edythe Broad Center of Regeneration Medicine, University of California, San Francisco, CA 94143, USA. Electronic address: jason.pomerantz@ucsf.edu.
University of California, San Francisco · US

Funding

Promoting Research Opportunities Fully--Prospective Academics Transforming HealthR25MD006832 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARONSON, LOUISE, FERNANDEZ, ALICIA · 2011 to 2015
$1.7M
NIMHD NIH HHS R25 MD006832
6 · The paper itself

Abstract

Investigation of human muscle regeneration requires robust methods to purify and transplant muscle stem and progenitor cells that collectively constitute the human satellite cell (HuSC) pool. Existing approaches have yet to make HuSCs widely accessible for researchers, and as a result human muscle stem cell research has advanced slowly. Here, we describe a robust and predictable HuSC purification process that is effective for each human skeletal muscle tested and the development of storage protocols and transplantation models in dystrophin-deficient and wild-type recipients. Enzymatic digestion, magnetic column depletion, and 6-marker flow-cytometric purification enable separation of 10

Indexed as

AnimalsCells, CulturedCell SeparationDystrophinHumansMiceMuscle, SkeletalRegenerationSatellite Cells, Skeletal MuscleStem CellsStem Cell TransplantationTransplantation, HeterologousDystrophinhuman satellite cell purificationsatellite cell cryopreservationserial transplantation

Identifiers

PMID29478895
PMCPMC5918346
OpenAlexW2788382771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.