ReviewDental clinics of North America2018
Fluorides and Other Preventive Strategies for Tooth Decay.
Review in Dental clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06403371 (The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients), which is not on this map. Cited by 68 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients: Prospective Randomized Controlled Clinical Trial
Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Topical fluoride-antibacterial agent combined therapy versus topical fluoride monotherapy in preventing dental caries: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020Pooled it
- Retention and caries-preventive outcomes of glass ionomer-based fissure sealants in children: a 24-month split-mouth randomized controlled trial.Scientific reports · 2026Trial
- A Randomized Clinical Trial Preventive Outreach Targeting Dental Caries and Oral-Health-Related Quality of Life for Refugee Children.International journal of environmental research and public health · 2021Trial
- Periodontal Disease and Edentulism Trends in Older Women of China and Association of Southeast Asian Nations, 1990 to 2033.International dental journal · 2026Article
- The Role of Moringa oleifera in Caries Prevention and Enamel Remineralization.European journal of dentistry · 2026Article
- Navigating fluoride hesitancy: mapping the evidence base for fluoride-free toothpaste alternatives.European journal of pediatrics · 2026Review
- Assessment of the remineralizing potential of nano-bioactive glass, nano-hydroxyapatite, and sodium fluoride on artificial carious lesions in primary teeth.BMC oral health · 2026Article
- Oral Self-Care as a Preventive Strategy in Medicated Older Adults: Biological Mechanisms, Genetic Susceptibility, and Public Health Implications.Healthcare (Basel, Switzerland) · 2026Review
- Fingerroot Extract Oral Spray for Anticariogenic Purpose: Integration of Ultrasound-Assisted Extraction and Solvent System Optimization.Advances in pharmacological and pharmaceutical sciences · 2026Article
- Community water fluoridation policy and population oral health: a policy analysis.Frontiers in oral health · 2026Review
- Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions.European oral research · 2026Article
- Effects of papain-based gel and air-abrasion enamel pretreatments on microleakage, sealant penetration, and shear bond strength of fissure sealant materials: anFrontiers in dental medicine · 2026Article
- The economic consequences of oral disorders at global, regional, and national levels.BMC oral health · 2025Article
- Challenges and solutions in managing dental problems in children with autism.World journal of clinical pediatrics · 2025Article
- Article
- Global prevalence of dental caries in the older people, 1991 to 2024: a systematic review and meta-analysis.The Saudi dental journal · 2025Review
- Article
- Assessment of Retention and Penetration Depth of Different Pit and Fissure Sealants: AnJournal of pharmacy & bioallied sciences · 2025Article
- A Review of Early Childhood Caries: Risk Factors, Management, and Policy Recommendations.Cureus · 2025Review
- AnJournal of pharmacy & bioallied sciences · 2025Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
We focus on scalable public health interventions that prevent and delay the development of caries and enhance resistance to dental caries lesions. These interventions should occur throughout the life cycle, and need to be age appropriate. Mitigating disease transmission and enhancing resistance are achieved through use of various fluorides, sugar substitutes, mechanical barriers such as pit-and-fissure sealants, and antimicrobials. A key aspect is counseling and other behavioral interventions that are designed to promote use of disease transmission-inhibiting and tooth resistance-enhancing agents. Advocacy for public water fluoridation and sugar taxes is an appropriate dental public health activity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.