ArticleEuropean journal of nuclear medicine and molecular imaging2018
Japanese multicenter database of healthy controls for [
Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Kinetic-rest tremor dominance for differentiating dystonic tremor from Parkinson's disease.Journal of Parkinson's disease · 2026Article
- Parkinsonism in Idiopathic Normal Pressure Hydrocephalus or Hydrocephalic Presentation in Parkinson's Disease: A Report of Three Cases.Internal medicine (Tokyo, Japan) · 2026Article
- Spectral presaturation with inversion recovery provides superior neuromelanin imaging for Parkinson's disease evaluation compared to magnetization transfer.Neuroradiology · 2026Article
- Sex-Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis.Annals of clinical and translational neurology · 2026Article
- Pupillary responses to the glare illusion in normal pressure hydrocephalus: insights into network dysfunction and neurodegenerative comorbidities.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Phase II pilot randomized trial of zonisamide for disease modification in prodromal Lewy body disease.NPJ Parkinson's disease · 2025Article
- When Age Is More Than a Number: Acceleration of Brain Aging in Neurodegenerative Diseases.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Utility of a newly created questionnaire on subtle motor symptoms in high-risk subjects with Parkinson's disease.Journal of Parkinson's disease · 2025Article
- Article
- Quantitative evaluation of striatal uptake ratios using an adaptive template registration method forAnnals of nuclear medicine · 2024Article
- α-synuclein seed amplification assay sensitivity may be associated with cardiac MIBG abnormality among patients with Lewy body disease.NPJ Parkinson's disease · 2024Article
- Plasma biomarkers of neurodegeneration in patients and high risk subjects with Lewy body disease.NPJ Parkinson's disease · 2024Article
- Potential dopaminergic deficit in patients with geriatric psychiatric disorders as revealed by DAT-SPECT: a cross-sectional study.BMJ mental health · 2024Article
- Long-term follow-up study of SWEDD patients with mild parkinsonian signs.BMJ neurology open · 2024Article
- Diagnostic Sensitivity and Symptomatic Relevance of Dopamine Transporter Imaging and Myocardial Sympathetic Scintigraphy in Patients with Dementia with Lewy Bodies.Journal of Alzheimer's disease : JAD · 2024Article
- Harmonizing multisite data with the ComBat method for enhanced Parkinson's disease diagnosis via DAT-SPECT.Frontiers in neurology · 2024Article
- Two distinct degenerative types of nigrostriatal dopaminergic neuron in the early stage of parkinsonian disorders.Clinical parkinsonism & related disorders · 2024Article
- Verification of optimal conditions for the scattering correction ofRadiological physics and technology · 2023Article
- No impact of attenuation and scatter correction on the interpretation of dopamine transporter SPECT in patients with clinically uncertain parkinsonian syndrome.European journal of nuclear medicine and molecular imaging · 2023Article
- Effect of cerebrospinal fluid area mask correction onBMC medical imaging · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this multicenter trial was to generate a [
methodsThis study included 510 sets of SPECT data from 256 healthy controls (116 men and 140 women; age range, 30-83 years) acquired from eight different centers. Images were reconstructed without attenuation or scatter correction (NOACNOSC), with only attenuation correction using the Chang method (ChangACNOSC) or X-ray CT (CTACNOSC), and with both scatter and attenuation correction using the Chang method (ChangACSC) or X-ray CT (CTACSC). These SPECT images were analyzed using the Southampton method. The outcome measure was the specific binding ratio (SBR) in the striatum. These striatal SBRs were calibrated from prior experiments using a striatal phantom.
resultsThe original SBRs gradually decreased in the order of ChangACSC, CTACSC, ChangACNOSC, CTACNOSC, and NOACNOSC. The SBRs for NOACNOSC were 46% lower than those for ChangACSC. In contrast, the calibrated SBRs were almost equal under no scatter correction (NOSC) conditions. A significant effect of age was found, with an SBR decline rate of 6.3% per decade. In the 30-39 age group, SBRs were 12.2% higher in women than in men, but this increase declined with age and was absent in the 70-79 age group.
conclusionsThis study provided a large-scale quantitative database of [
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