Evidence map›Paper›PMID 29478081›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI.

N A da Silva, P Lohmann, J Fairney, A W Magill, A-M Oros Peusquens, C-H Choi, R Stirnberg, G Stoffels, N Galldiks, X Golay and 2 more

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CEST MRI provides amide/amine surrogate biomarkers for treatment-naïve glioma sub-typing.European journal of nuclear medicine and molecular imaging · 2022
    Article
  6. Article
  7. Review
  8. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

N A da SilvaInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
P LohmannInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
J FairneyDepartment of Medical Physics & Biomedical Engineering, University College London, London, London, UK.
A W MagillInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
A-M Oros PeusquensInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
C-H ChoiInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
R StirnbergInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
G StoffelsInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
N GalldiksInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
X GolayDepartment of Medical Physics & Biomedical Engineering, University College London, London, London, UK.
K-J LangenInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
N Jon ShahInstitute of Neuroscience and Medicine, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany. n.j.shah@fz-juelich.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePET using radiolabelled amino acids has become a promising tool in the diagnostics of gliomas and brain metastasis. Current research is focused on the evaluation of amide proton transfer (APT) chemical exchange saturation transfer (CEST) MR imaging for brain tumour imaging. In this hybrid MR-PET study, brain tumours were compared using 3D data derived from APT-CEST MRI and amino acid PET using O-(2-

methodsEight patients with gliomas were investigated simultaneously with

resultsA tumour-to-brain ratio derived from APT# and

conclusionFor the first time, CEST images were compared with

Indexed as

Proton Magnetic Resonance SpectroscopyAdultAgedBrain NeoplasmsFemaleGliomaHumansMaleMiddle AgedProtonsTyrosineYoung AdultProtonsTyrosine18F-FET PETAPTCESTGliomaHybrid MR-PET

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.