Evidence map›Paper›PMID 29478022›Full record

Observational studyJournal of the American Heart Association2018

Physical Activity Measured by Implanted Devices Predicts Atrial Arrhythmias and Patient Outcome: Results of IMPLANTED (Italian Multicentre Observational Registry on Patients With Implantable Devices Remotely Monitored).

Pietro Palmisano, Federico Guerra, Ernesto Ammendola, Matteo Ziacchi, Ennio Carmine Luigi Pisanò, Gabriele Dell'Era, Vittorio Aspromonte, Maria Zaccaria, Francesco Di Ubaldo, Alessandro Capucci and 7 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 2 countries.

Pietro PalmisanoCardiology Unit "Card. G. Panico" Hospital, Tricase, Italy dr.palmisano@libero.it.
Federico GuerraCardiology and Arrhythmology Clinic, Marche Polytechnic University University Hospital "Umberto I-Lancisi-Salesi,", Ancona, Italy.
Ernesto AmmendolaDepartment of Cardiology, Monaldi Hospital Second University of Naples, Italy.
Matteo ZiacchiInstitute of Cardiology, University of Bologna S.Orsola-Malpighi University Hospital, Bologna, Italy.
Ennio Carmine Luigi Pisanò"Vito Fazzi" Hospital, Lecce, Italy.
Gabriele Dell'EraDivision of Cardiology, University of Eastern Piedmont Maggiore della Carità Hospital, Novara, Italy.
Vittorio AspromonteCardiology-Coronary Care Unit, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
Maria ZaccariaCardiology Unit "Card. G. Panico" Hospital, Tricase, Italy.
Francesco Di UbaldoCardiology and Arrhythmology Clinic, Marche Polytechnic University University Hospital "Umberto I-Lancisi-Salesi,", Ancona, Italy.
Alessandro CapucciCardiology and Arrhythmology Clinic, Marche Polytechnic University University Hospital "Umberto I-Lancisi-Salesi,", Ancona, Italy.
Gerardo NigroDepartment of Cardiology, Monaldi Hospital Second University of Naples, Italy.
Eraldo OcchettaDivision of Cardiology, University of Eastern Piedmont Maggiore della Carità Hospital, Novara, Italy.
Giampiero MagliaCardiology-Coronary Care Unit, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
Renato Pietro RicciDepartment of Cardiovascular Diseases, San Filippo Neri Hospital, Rome, Italy.
Giuseppe BorianiCardiology Department, University of Modena and Reggio Emilia Policlinico di Modena, Italy.
Michele AccogliCardiology Unit "Card. G. Panico" Hospital, Tricase, Italy.
Italian Association of Arrhythmology and Cardiac Pacing (AIAC)
Govind Ballabh Pant Hospital · INMarche Polytechnic University · ITAzienda Ospedaliera Pugliese Ciaccio · ITOspedale Vito Fazzi · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITOspedale Monaldi · ITOspedale San Filippo Neri · ITPoliclinico di Modena · ITUniversity of Bologna · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine whether daily physical activity (PA), as measured by implanted devices (through accelerometer sensor), was related to the risk of developing atrial arrhythmias during long-term follow-up in a population of heart failure (HF) patients with an implantable cardioverter defibrillator (ICD). METHODS AND

resultsThe study population was divided into 2 equally sized groups (PA cutoff point: 3.5 h/d) according to their mean daily PA recorded by the device during the 30- to 60-day period post-ICD implantation. Propensity score matching was used to compare 2 equally sized cohorts with similar characteristics between lower and higher activity patients. The primary end point was time free from the first atrial high-rate episode (AHRE) of duration ≥6 minutes. Secondary end points were: first AHRE ≥6 hours, first AHRE ≥48 hours, and a combined end point of death or HF hospitalization. Data from 770 patients (65±15 years; 66% men; left ventricular ejection fraction 35±12%) remotely monitored for a median of 25 months were analyzed. A PA ≥3.5 h/d was associated with a 38% relative reduction in the risk of AHRE ≥6 minutes (72-month cumulative survival: 75.0% versus 68.1%; log rank

conclusionsIn HF patients with ICD, a low level of daily PA was associated with a higher risk of atrial arrhythmias, regardless of the patients' baseline characteristics. In addition, a lower daily PA predicted death or HF hospitalization.

Indexed as

Defibrillators, ImplantableExerciseFitness TrackersActigraphyAgedAged, 80 and overAtrial FibrillationElectric CountershockFemaleHealth StatusHeart FailureHumansItalyMaleMiddle AgedPredictive Value of Testsatrial fibrillationheart failureimplanted cardioverter defibrillatorphysical exercise

Identifiers

PMID29478022
PMCPMC5866336
OpenAlexW2790644628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.