ArticleBMJ case reports2018
Pleuroparenchymal fibroelastosis with positive MPO-ANCA diagnosed with a CT-guided percutaneous needle biopsy.
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Korean Guidelines for the Diagnosis and Management of Interstitial Lung Disease: Other Forms of Interstitial Lung Disease.Tuberculosis and respiratory diseases · 2025Article
- [Pleural Metastasis of Lung Cancer Combined with Pleuroparenchymal Fibroelastosis: A Case Report].Journal of the Korean Society of Radiology · 2024Article
- Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.Annals of the American Thoracic Society · 2019Review
- Pleuroparenchymal fibroelastosis (PPFE) treated with lung transplantation and review of the literature.BMJ case reports · 2019Review
- Pleuroparenchymal fibroelastosis as a histological background of autoimmune diseases.Virchows Archiv : an international journal of pathology · 2019Article
- Pleuroparenchymal fibroelastosis from a rheumatologic perspective.Therapeutic advances in respiratory diseaseArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 67-year-old woman was referred to our hospital because of gradually increasing dyspnoea on exertion for 6 months. Chest CT scan showed subpleural parenchymal fibrotic opacities with traction bronchiectasis in the bilateral upper lung fields. Serum rheumatoid factor and myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) were positive. There was no evident reason to suspect connective tissue disease such as ANCA-associated vasculitis or rheumatoid arthritis. We performed a CT-guided percutaneous needle biopsy of the subpleural lesion that showed slight uptake on the fluorodeoxyglucose-positron emission tomography (FDG-PET) CT scan. This specimen showed subpleural fibrosis as evidenced by an abnormal increase of elastic tissue and minimal collagen deposition, which indicated pleuroparenchymal fibroelastosis (PPFE). Although PPFE can be associated with a variety of causes, its association with MPO-ANCA is unknown. A CT-guided transthoracic lung biopsy caused no adverse events and was useful in the diagnosis of PPFE in our patient.
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