Evidence map›Paper›PMID 29477718›Full record

ArticleThe Journal of urology2018

Prevalence and Characteristics of Urinary Incontinence in a Treatment Seeking Male Prospective Cohort: Results from the LURN Study.

Brian T Helfand, Abigail R Smith, H Henry Lai, Claire C Yang, John L Gore, Brad A Erickson, Karl J Kreder, Anne P Cameron, Kevin P Weinfurt, James W Griffith and 5 more

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062875 (Effects of TNF Blockade on Human BPH/LUTS), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062875 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Effects of TNF Blockade on Human BPH/LUTS

TypeinterventionalSponsorEndeavor HealthRan2024 to 2028Enrolled70ConditionsBenign Prostatic Hyperplasia (BPH)ArmsAdalimumab
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Review
  17. Urinary Incontinence: Epidemiology and Physiotherapeutic Approaches- A Systematic Review.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Brian T HelfandNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland. Electronic address: bhelfand@northshore.org.
Abigail R SmithNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
H Henry LaiNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Claire C YangNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
John L GoreNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Brad A EricksonNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Karl J KrederNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Anne P CameronNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Kevin P WeinfurtNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
James W GriffithNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Aaron LentzNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Pooja TalatyNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Victor P AndreevNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Ziya KirkaliNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
LURNNorthShore University Health System (BTH, PT), Evanston, Illinois; Feinberg School of Medicine, Northwestern University (JWG), Chicago, Illinois; Arbor Research Collaborative for Health (ARS, VPA), Ann Arbor, Michigan; University of Michigan (APC), Ann Arbor, Michigan; Washington University School of Medicine (HHL), St. Louis, Missouri; University of Washington (CCY, JLG), Seattle, Washington; Department of Urology, University of Iowa (KJK), Iowa City, Iowa; Duke University Medical Center (KPW, AL), Durham, North Carolina; National Institute of Diabetes and Digestive and Kidney Diseases (ZK), Bethesda, Maryland.
Washington University in St. Louis · USUniversity of Michigan–Ann Arbor · USArbor Research Collaborative for Health · USNorthwestern University · USNorthShore University HealthSystem · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating CenterU24DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI GRAFF, JOHN JOSEPH · 2019 to 2025
$6.9M
Phenotype of urinary symptoms and relationships with genotype, sleep and obesityU01DK097779 · NIDDK · UNIVERSITY OF CHICAGO · PI GRIFFITH, JAMES WILLIAM, KENTON, KIMBERLY SUE · 2012 to 2025
$5.7M
Advancing the Measurement and Classification of Lower Urinary Tract DysfunctionU01DK097780 · NIDDK · DUKE UNIVERSITY · PI AMUNDSEN, CINDY, JELOVSEK, JOHN ERIC · 2012 to 2025
$5.3M
University of Iowa LURN Research SiteU01DK097772 · NIDDK · UNIVERSITY OF IOWA · PI BRADLEY, CATHERINE S, KREDER, KARL J · 2012 to 2025
$5.0M
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)U01DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2013 to 2018
$4.6M
University of Washington LURN Research SiteU01DK100011 · NIDDK · UNIVERSITY OF WASHINGTON · PI YANG, CLAIRE C · 2013 to 2025
$4.5M
University of Michigan LURN Research SiteU01DK099932 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLEMENS, J. QUENTIN · 2013 to 2023
$4.4M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Second Phase StudyU01DK100017 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2013 to 2025
$3.9M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)Data CoordinatU01DK097776 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2012 to 2016
$1.7M
NCATS NIH HHS UL1 TR001422NIDDK NIH HHS U01 DK097772NIDDK NIH HHS U01 DK097776NIDDK NIH HHS U01 DK097779NIDDK NIH HHS U01 DK097780NIDDK NIH HHS U01 DK099879NIDDK NIH HHS U01 DK099932NIDDK NIH HHS U01 DK100011NIDDK NIH HHS U01 DK100017NIDDK NIH HHS U24 DK099879
6 · The paper itself

Abstract

purposeMale urinary incontinence is thought to be infrequent. We sought to describe the prevalence of urinary incontinence in a male treatment seeking cohort enrolled in the LURN (Symptoms of Lower Urinary Tract Dysfunction Research Network). MATERIALS AND

methodsStudy inclusion and exclusion criteria, including men with prostate cancer or neurogenic bladder, were previously reported. LURN participants prospectively completed questionnaires regarding lower urinary tract symptoms and other clinical variables. Men were grouped based on incontinence type, including 1) no urinary incontinence, 2) post-void dribbling only and 3) urinary incontinence. Comparisons were made using ANOVA and multivariable regression.

resultsOf the 477 men 24% reported no urinary incontinence, 44% reported post-void dribbling only and 32% reported urinary incontinence. African American men and those with sleep apnea were more likely to be in the urinary incontinence group than in the no urinary incontinence group (OR 3.2, p = 0.02 and OR 2.73, p = 0.003, respectively). Urinary incontinence was associated with significantly higher bother compared to men without leakage (p <0.001). Compared to men without urinary incontinence and men with only post-void dribbling those with urinary incontinence were significantly more likely to report higher scores (more severe symptoms) on the PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaires regarding bowel issues, depression and anxiety than men without urinary incontinence (p <0.01).

conclusionsUrinary incontinence is common among treatment seeking men. This is concerning because the guideline recommended questionnaires to assess male lower urinary tract symptoms do not query for urinary incontinence. Thus, clinicians may be missing an opportunity to intervene and improve patient care. This provides a substantial rationale for a new or updated symptom questionnaire which provides a more comprehensive symptom assessment.

Indexed as

AgedAnxietyComorbidityDepressionHealth Services Needs and DemandHumansMaleMiddle AgedPractice Guidelines as TopicPrevalenceProspective StudiesQuality of LifeSleep Apnea SyndromesSurveys and QuestionnairesUrinary IncontinenceUrologylower urinary tract symptomsneurogenicprostatic neoplasmssurveys and questionnairesurinary bladderurinary incontinence

Identifiers

PMID29477718
PMCPMC6145092
OpenAlexW2788517816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.