ArticleMedicina oral, patologia oral y cirugia bucal2018
Hematinic deficiencies in patients with recurrent aphthous stomatitis: variations by gender and age.
Article in Medicina oral, patologia oral y cirugia bucal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Hematological parameters in patients with recurrent Aphthous Stomatitis: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Vitamin D deficiency and risk of recurrent aphthous stomatitis: updated meta-analysis with trial sequential analysis.Frontiers in nutrition · 2023Pooled it
- Association between serum zinc levels and recurrent aphthous stomatitis: a meta-analysis with trial sequential analysis.Clinical oral investigations · 2021Pooled it
- Single application of topical doxycycline in management of recurrent aphthous stomatitis: a systematic review and meta-analysis of the available evidence.BMC oral health · 2020Pooled it
- Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study.BMC oral health · 2025Article
- Beyond the Gut: A Systematic Review of Oral Manifestations in Celiac Disease.Journal of clinical medicine · 2023Review
- Vitamin B12 deficiency may play an etiological role in atrophic glossitis and its grading: A clinical case-control study.BMC oral health · 2022Article
- Relationship between dietary factors and recurrent aphthous stomatitis in China: a cross-sectional study.The Journal of international medical research · 2021Article
- The Impact of DNA Methylation on IL6 mRNA Levels in Hematinic Deficiency and Atopy-Associated Recurrent Aphthous Stomatitis Patients.International journal of dentistry · 2021Article
- The profile of hematinic deficiencies in patients with oral lichen planus: a case-control study.BMC oral health · 2020Article
- Penicillin in oral aphthosis, new insight for an old drug: A randomized, double-blind, controlled clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020Article
- Systemic immune inflammation index in patients with recurrent aphthous stomatitis.Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate the association between hematinic deficiencies and recurrent aphthous stomatitis (RAS). MATERIAL AND
methods517 RAS patients and 187 healthy controls were enrolled in the present study. Hematinic deficiencies, including serum ferritin, folic acid, and vitamin B12 deficiencies were assessed for each participant. Gender and age were taken into account and the collected data were statistically analysed.
resultsCompared with the healthy controls, a significantly higher overall frequency of hematinic deficiencies was found in RAS patients (p<0.001). When gender and age were taken into account, significant differences in hematinic deficiencies were observed among RAS patients. Serum ferritin deficiency was much more common in young and middle-aged female RAS patients (age<60). Serum folate deficiency and serum vitamin B12 deficiency were both much more common in the young adult group of male RAS patients (21-40 years of age). Logistic regression analysis revealed that both gender and age have significant correlation with the presence of hematinic deficiencies in the RAS patients.
conclusionSignificant variations in hematinic deficiencies were demonstrated in RAS patients across different genders and age groups. We suggest that further studies on the hematinic deficiencies of RAS patients should take into account the gender and age of participants.
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