Evidence map›Paper›PMID 29476479›Full record

ArticleNeuromolecular medicine2018

Vitamin D

Megan A Evans, Hyun Ah Kim, Yeong Hann Ling, Sandy Uong, Antony Vinh, T Michael De Silva, Thiruma V Arumugam, Andrew N Clarkson, Graeme R Zosky, Grant R Drummond and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Neuromolecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. CD4Frontiers in immunology · 2025
    Review
  13. Role of vitamin DToxicology research · 2024
    Article
  14. Review
  15. Th17 Cells and IL-17A in Ischemic Stroke.Molecular neurobiology · 2024
    Review
  16. Frontiers in cellular neuroscience · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Megan A EvansVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
Hyun Ah KimVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
Yeong Hann LingVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
Sandy UongCardiovascular Disease Program, Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.
Antony VinhVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
T Michael De SilvaVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
Thiruma V ArumugamDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.
Andrew N ClarksonDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, 9054, New Zealand.
Graeme R ZoskySchool of Medicine, Faculty of Health Science, University of Tasmania, Hobart, TAS, 7005, Australia.
Grant R DrummondVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia.
Brad R S BroughtonCardiovascular Disease Program, Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.
Christopher G SobeyVascular Biology Immunopharmacology Group, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, VIC, 3083, Australia. c.sobey@latrobe.edu.au.
Australian Regenerative Medicine Institute · AUMonash University · AULa Trobe University · AUNational University of Singapore · SGUniversity of Otago · NZUniversity of Tasmania · AU

Funding

National Health and Medical Research Council APP1079467
6 · The paper itself

Abstract

Acute inflammation can exacerbate brain injury after ischemic stroke. Beyond its well-characterized role in calcium metabolism, it is becoming increasingly appreciated that the active form of vitamin D, 1,25-dihydroxyvitamin D

Indexed as

AnimalsBrainCholecalciferolCytokinesForkhead Transcription FactorsGene Expression RegulationInfarction, Middle Cerebral ArteryInflammationInflammation MediatorsMacrophagesMaleMice, Inbred C57BLMicrogliaMotor ActivityNerve Tissue ProteinsNeuroprotective AgentsCholecalciferolCytokinesForkhead Transcription FactorsFoxp3 protein, mouseInflammation MediatorsNerve Tissue ProteinsNeuroprotective AgentsNuclear Receptor Subfamily 1, Group F, Member 3Rorc protein, mouseInflammationMiddle cerebral artery occlusionMouseStrokeVitamin D

Identifiers

PMID29476479
PMCPMC5834596
OpenAlexW2788988673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.