Evidence map›Paper›PMID 29476358›Full record

ReviewCurrent pain and headache reports2018

The Opioid Crisis: a Comprehensive Overview.

Nalini Vadivelu, Alice M Kai, Vijay Kodumudi, Julie Sramcik, Alan D Kaye

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04942561 (Effect of Immersive Virtual Reality on Pain and Anxiety in Pediatric Peripheral Intravenous Catheter Access), which is not on this map. Cited by 131 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 6 pooled it
27.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04942561 nacompletednot on this map

Effect of Immersive Virtual Reality on Pain and Anxiety in Pediatric Peripheral Intravenous Catheter Access: A Randomized Clinical Trial

TypeinterventionalSponsorChildren's Hospital Los AngelesRan2017 to 2019Enrolled107ConditionsRadiologyArmsSamsung Gear VR, Merge VR
3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 6 syntheses or guidelines pooled it, 255 citations in OpenAlex.

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  11. The Reverse Risk Register Approach to Understanding Systemic Factors in Risk Analysis and Management Case Studies.Risk analysis : an official publication of the Society for Risk Analysis · 2026
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Nalini VadiveluDepartment of Anesthesiology, Yale University, TMP3 333, Cedar Street, New Haven, CT, 06520, USA. nalini.vadivelu@yale.edu.
Alice M KaiDepartment of Internal Medicine, NYU Winthrop Hospital, 259 First Street, Mineola, NY, 11501, USA.
Vijay KodumudiMedical Student, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT, 06030-1905, USA.
Julie SramcikDepartment of Anesthesiology, Yale University, TMP3 333, Cedar Street, New Haven, CT, 06520, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, 1542 Tulane Ave, Suite 656, New Orleans, LA, 70112, USA.
Yale University · USLouisiana State University Health Sciences Center New Orleans · USUniversity of Connecticut · USWinthrop-University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe opioid crisis most likely is the most profound public health crisis our nation has faced. In 2015 alone, 52,000 people died of drug overdoses, with over 30,000 of those people dying from opioid drugs. A recent community forum led by the Cleveland Clinic contrasted this yearly death rate with the loss of 58,000 American lives in 4 years of the Vietnam War. The present review describes the origins of this opioid epidemic and provides context for our present circumstances. RECENT

findingsAlarmingly, the overwhelming majority of opioid abusers begin their addiction with prescription medications, primarily for chronic pain. Chronic postoperative pain, which occurs in 10-50% of surgical patients, is a major concern in many types of surgery. Nationwide, the medical community has made it a priority to ensure that postsurgical analgesia is sufficient to control pain without increasing non-medically appropriate opioid use. The opioid epidemic remains a significant pressing issue and will not resolve easily. Numerous factors, including the inappropriate prescription of opioids, lack of understanding of the potential adverse effects of long-term therapy, opioid misuse, abuse, and dependence, have contributed to the current crisis.

Indexed as

Opioid-Related DisordersChronic PainHumansPrescription Drug MisuseUnited StatesHealth policyOpioidsOverdose deathsPain

Identifiers

PMID29476358
OpenAlexW2790657788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.