ReviewCurrent pain and headache reports2018
Migraine and Autonomic Dysfunction: Which Is the Horse and Which Is the Jockey?
Review in Current pain and headache reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04628429 (Autonomic Functions in Migraine Patients as a Function of Migraine Status and CGRP Inhibition), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Autonomic Functions in Migraine Patients as a Function of Migraine Status and CGRP Inhibition
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Reconceptualizing autonomic function testing in migraine: a systematic review and meta-analysis.The journal of headache and pain · 2024Pooled it
- Effect of comorbid migraine on propranolol efficacy for painful TMD in a randomized controlled trial.Cephalalgia : an international journal of headache · 2021Trial
- Quantitative pupillometry as a marker of autonomic dysregulation in vestibular migraine.Journal of oral & facial pain and headache · 2026Article
- Wearable Nocturnal Autonomic and Sleep Biomarkers for Predicting Next-Day Headache and Identifying Nociplastic Pain in Patients with Migraine.Journal of clinical medicine · 2026Article
- A Holistic and Dynamic Network-Level View of the Autonomic Nervous System.Annual review of biomedical engineering · 2026Review
- Bridging the gap: molecular mechanisms, regional activity and connectivity in headache disorders.Brain : a journal of neurology · 2026Review
- P-Wave dispersion and atrial conduction abnormalities in migraine: implications for cardiovascular risk.Acta neurologica Belgica · 2026Article
- Mid-term Electrical Remodelling in Surface ECG Following Percutaneous Patent Foramen Ovale Closure.Interventional cardiology (London, England) · 2026Article
- Can smartwatches predict migraines?Research square · 2025Article
- Unforeseen beneficial effect of successful PVC ablation: Achieving migraine attack control without medication.Journal of arrhythmia · 2025Article
- Mechanisms and clinical applications of the valsalva maneuver in migraine relief: A mini-review.Current journal of neurology · 2025Article
- From the latin "re-cordis, passing through the heart": autonomic modulation differentiates migraineurs from controls when recounting a significant life event.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- The Near Point of Convergence in Patients with Vestibular Migraine.International archives of otorhinolaryngology · 2025Article
- Neurological Disorders in Takotsubo Syndrome: Clinical Phenotypes and Outcomes.Journal of the American Heart Association · 2024Article
- Electrocardiogram Features in Non-Cardiac Diseases: From Mechanisms to Practical Aspects.Journal of multidisciplinary healthcare · 2024Review
- The Gut-brain Connection and Episodic Migraine: an Update.Current pain and headache reports · 2023Review
- Sub-occipital muscle pressure pain thresholds correlate to direction of symptomatic active comfortable sustained neck rotation testing in post-concussive headache: a retrospective observational cross-sectional study.The Journal of manual & manipulative therapy · 2023Observational
- "The Pupillary (Hippus) Nystagmus": A Possible Clinical Hallmark to Support the Diagnosis of Vestibular Migraine.Journal of clinical medicine · 2023Article
- Cranial Autonomic Symptoms and Neck Pain in Differential Diagnosis of Migraine.Diagnostics (Basel, Switzerland) · 2023Review
- Accurate Diagnosis and Treatment of Painful Temporomandibular Disorders: A Literature Review Supplemented by Own Clinical Experience.Pain research & management · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewSymptoms of autonomic dysfunction are common in patients with migraine, both during and between migraine attacks. Studies evaluating objective autonomic testing in patients have found significant, though somewhat conflicting results. The purposes of this review are to summarize and interpret the key findings of these studies, including those evaluating heart rate variability, autonomic reflex testing, and functional imaging in patients with migraine. The neuroanatomy of the central autonomic network as it relates to migraine is also reviewed. RECENT
findingsSeveral studies have evaluated autonomic balance in migraineurs, with conflicting results on the magnitude of sympathetic versus parasympathetic dysfunction. Most studies demonstrate sympathetic impairment, with a lesser degree of parasympathetic impairment. Three trends have emerged: (1) migraine with aura tends to produce more significant autonomic dysfunction than migraine without aura, (2) sympathetic impairment is more common than parasympathetic impairment, and (3) sympathetic impairment is common in the interictal period, with increased sympathetic responsiveness during the ictal period, suggesting adrenoreceptor hypersensitivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.