ArticleScientific reports2018
Semi-quantitative Analysis of EBUS Elastography as a Feasible Approach in Diagnosing Mediastinal and Hilar Lymph Nodes of Lung Cancer Patients.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 19 citations in OpenAlex.
- Evaluation of diagnostic accuracy and molecular adequacy between conventional endobronchial ultrasound, contrast-enhanced endobronchial ultrasound and elastography for hilar and mediastinal lymphadenopathies: a retrospective observational study.Journal of thoracic disease · 2026Article
- Diagnostic utility of endobronchial ultrasound elastography for detecting benign and malignant lymph nodes: a retrospective study.Journal of thoracic disease · 2025Article
- Clinical utility of artificial intelligence-augmented endobronchial ultrasound elastography in lymph node staging for lung cancer.JTCVS techniques · 2024Article
- Diagnostic value of endobronchial ultrasound elastography in differentiating between benign and malignant hilar and mediastinal lymph nodes: a retrospective study.Quantitative imaging in medicine and surgery · 2023Article
- Quantitative analysis of endobronchial elastography combined with serum tumour markers of lung cancer in the diagnosis of benign and malignant mediastinal and hilar lymph nodes.Pathology oncology research : POR · 2023Article
- Ultrasound Elastography for the Evaluation of Lymph Nodes.Frontiers in oncology · 2021Review
- Quantitative analysis of endobronchial ultrasound elastography in computed tomography-negative mediastinal and hilar lymph nodes.Thoracic cancer · 2020Article
- [Current Status and Development of Interventional Techniques for Pulmonary Diseases].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2020Review
- The role of endobronchial ultrasonography elastography for predicting malignancy.Turk gogus kalp damar cerrahisi dergisi · 2020Article
- Guidelines for endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA): Joint Indian Chest Society (ICS)/Indian Association for Bronchology (IAB) recommendations.Lung India : official organ of Indian Chest SocietyArticle
- Diagnostic value of endobronchial ultrasound image features: A specialized review.Endoscopic ultrasoundReview
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Authors and funding
10 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
This study aimed to semi-quantitatively evaluate the elastographic imaging color distribution of mediastinal and hilar lymph nodes (LNs), and explored its utility in helping define malignant and benign LNs for lung cancer patients. We prospectively collected patients who underwent preoperative mediastinal staging of suspected lung cancer by EBUS-TBNA. We analyzed the elastography color distribution of each LN and calculated the blue color proportion (BCP). The LN elastographic patterns were compared with the final EBUS-TBNA pathological results. A receiver operating characteristic (ROC) curve was constructed to evaluate the diagnostic value of BCP. We sampled and analyzed 79 LNs from 60 patients. The average BCP in malignant LNs was remarkably higher than that in benign LNs (57.1% versus 30.8%, P < 0.001). The area under the ROC curve (AUC) for the BCP was 0.86 (95% CI: 0.78-0.94). The best cutoff BCP for differentiating between benign and malignant LNs was determined as 36.7%. All the 16 LNs (20.3%) with a BCP lower than 27.9% were diagnosed as benign tissues. Our study suggests that elastography is a feasible technique that may safely help to predict LN metastasis during EBUS-TBNA. We found a clear BCP cutoff value to help define positive and negative LNs.
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