Evidence map›Paper›PMID 29476152›Full record

ArticleNature cell biology2018

Recognition of RNA N

Huilin Huang, Hengyou Weng, Wenju Sun, Xi Qin, Hailing Shi, Huizhe Wu, Boxuan Simen Zhao, Ana Mesquita, Chang Liu, Celvie L Yuan and 20 more

Erratum issuedAbstract read
In one paragraph

Article in Nature cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1,897 papers.

0numbers the graph read from it
0cells of the map it votes in
1,897citing papers in PubMed
84.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,897 citing papers in PubMed, 3,042 citations in OpenAlex.

  1. NAR cancer · 2026
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1,837 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 8 institutions in 3 countries.

Huilin HuangDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Hengyou WengDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Wenju SunKey Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Xi QinDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Hailing ShiDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Huizhe WuDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Boxuan Simen ZhaoDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Ana MesquitaDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Chang LiuDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Celvie L YuanDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Yueh-Chiang HuDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-7992-0525
Stefan HüttelmaierInstitute of Molecular Medicine, Department of Molecular Cell Biology, Martin Luther University, Halle, Germany.
Jennifer R SkibbeDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Rui SuDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Xiaolan DengDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Lei DongDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Miao SunDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Chenying LiDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Sigrid NachtergaeleDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.
Yungui WangDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Chao HuDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Kyle FerchenDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Kenneth D GreisDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Xi JiangDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Minjie WeiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.
Lianghu QuKey Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Jun-Lin GuanDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Chuan HeDepartment of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424
Jianhua YangKey Laboratory of Gene Engineering of the Ministry of Education, Sun Yat-sen University, Guangzhou, China. yangjh7@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0003-3863-2786
Jianjun ChenDepartment of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. jianchen@coh.org.ORCID http://orcid.org/0000-0003-3749-2902
City of Hope · USHoward Hughes Medical Institute · USUniversity of Cincinnati Medical Center · USCincinnati Children's Hospital Medical Center · USSun Yat-sen University · CNFirst Affiliated Hospital Zhejiang University · CNChina Medical University · CNMartin Luther University Halle-Wittenberg · DE

Funding

Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Mechanisms of FIP200 regulation of breast cancer through its autophagy and non-autophagy functionsR01CA211066 · NCI · UNIVERSITY OF CINCINNATI · PI JUN-LIN GUAN · 2017 to 2026
$3.4M
Recognition and mechanism of N6-methyl adenosine modificationsR01GM113194 · NIGMS · UNIVERSITY OF CHICAGO · PI PAN, TAO · 2015 to 2022
$2.5M
The role and mechanism of METTL3/METTL14-mediated RNA modification in the pathogenesis and drug-resistance of AMLR01CA236399 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2019 to 2023
$2.3M
Targeting TET1 signaling to treat acute myeloid leukemiaR01CA211614 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.3M
The role and mechanism of FTO in leukemogenesis and drug responseR01CA214965 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.1M
Potential therapeutic implications of targeting miR-150 in acute myeloid leukemiaR01CA182528 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2014 to 2018
$1.7M
The role and functional mechanism of TET1 in MLL-rearranged leukemiaR01CA178454 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2014 to 2018
$1.7M
Genetic Analysis of FAK kinase and scaffold functions in breast cancerR01CA163493 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUAN, JUN-LIN · 2012 to 2016
$1.6M
Discovering the epigenetics of RNA modificationsR01GM088599 · NIGMS · UNIVERSITY OF CHICAGO · PI HE, CHUAN, PAN, TAO · 2009 to 2012
$1.2M
Enhanced proteomics capabilities for quantitation of proteins with a triple quadS10RR027015 · NCRR · UNIVERSITY OF CINCINNATI · PI GREIS, KENNETH DONALD · 2010 to 2010
$426k
Howard Hughes Medical InstituteNCI NIH HHS R01 CA163493NCI NIH HHS R01 CA178454NCI NIH HHS R01 CA182528NCI NIH HHS R01 CA211066NCI NIH HHS R01 CA211614NCI NIH HHS R01 CA214965NCI NIH HHS R01 CA236399NCRR NIH HHS S10 RR027015NHGRI NIH HHS RM1 HG008935NIGMS NIH HHS R01 GM088599NIGMS NIH HHS R01 GM113194
6 · The paper itself

Abstract

N

Indexed as

RNA Processing, Post-TranscriptionalRNA StabilityAdenosineBinding SitesCell MovementCell ProliferationConsensus SequenceFemaleFetal BloodGene Expression Regulation, NeoplasticHEK293 CellsHeLa CellsHematopoietic Stem CellsHep G2 CellsHumansLiver NeoplasmsAdenosineIGF2BP1 protein, humanIGF2BP2 protein, humanIGF2BP3 protein, humanN-methyladenosineRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID29476152
PMCPMC5826585
OpenAlexW2793785833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.