Evidence map›Paper›PMID 29476111›Full record

ArticleScientific reports2018

Protective effects of Chinese Fenggang zinc selenium tea on metabolic syndrome in high-sucrose-high-fat diet-induced obese rats.

Jie Yu, Jing Yang, Mizhuan Li, Xuesong Yang, Pan Wang, Jie Xu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jie YuSchool of Public Health, Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China.
Jing YangSchool of Public Health, Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China.
Mizhuan LiSchool of Public Health, Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China.
Xuesong YangSchool of Public Health, Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China.
Pan WangDepartment of Nuclear Medicine, The Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China.
Jie XuSchool of Public Health, Zunyi Medical University, Zunyi Guizhou, 563099, P.R. China. Xujie360@sina.com.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protective effect of zinc selenium tea against metabolic syndrome (MetS) was tested by using a high-sucrose-high-fat diet (HSHFD)-induced MetS model. Fifty Sprague-Dawley rats were randomly divided into five groups: normal diet (C-group), HSHFD (CH-group), HSHFD + green tea (0.24 g/kg/day) (TH-group), HSHFD + low-dose zinc selenium organic tea (0.24 g/kg/day) (ZTHL-group), and HSHFD + high-dose zinc selenium organic tea (1.20 g/kg/day) (ZTHH-group). After 8 weeks, compared to both the C-group and CH-group, the hepatosomatic index (HI) was significantly reduced in the ZTHL-group (p < 0.05). Fasting blood glucose (FBG) levels were highest in the TH-group, followed by the CH-group, then the ZTHL-group, then the ZTHH-group, and finally the C-group. Compared with the CH-group, the serum total cholesterol (TC) and low density lipid-cholesterol (LDL-C) concentrations were significantly lower in the ZTHH-group (p < 0.05). Significant decreases in serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bile acids (TBA), alkaline phosphatase (ALP), and direct bilirubin (DBIL) levels were observed in ZTHL-group versus the CH-group (p < 0.05). Serum alpha-L-fucosidase (AFU) levels in the ZTHH-group were lower than in the CH-group (P < 0.01). Histopathological examination of the liver and fat biopsies illustrates that the liver cells showed a decrease in the extent of necrosis and dropsy in the ZTHL-group and ZTHH-group versus the CH-group. Zinc selenium tea showed a protection effect against hepatic damage.

Indexed as

Adipose TissueAlanine TransaminaseAlkaline Phosphatasealpha-L-FucosidaseAnimalsAntioxidantsAspartate AminotransferasesBilirubinBlood GlucoseCholesterol, LDLDiet, High-FatDose-Response Relationship, DrugFastingFemaleHypoglycemic AgentsLiverAlanine TransaminaseAlkaline Phosphatasealpha-L-FucosidaseAntioxidantsAspartate AminotransferasesBilirubinBlood GlucoseCholesterol, LDLHypoglycemic AgentsSelenium CompoundsSucroseTeaZinc Compoundszinc selenite

Identifiers

PMID29476111
PMCPMC5824815
OpenAlexW2806910750

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.