ArticleNature communications2018
Cobalt-catalyzed electrooxidative C-H/N-H [4+2] annulation with ethylene or ethyne.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Cathodic oxygen reduction-enabled rhodium-catalyzed (5 + 1) C-H/O-H annulation inspired by fuel cells.Nature communications · 2025Article
- Mechanistic Investigations of Cobalt-Catalyzed, Aminoquinoline-Directed C(spJournal of the American Chemical Society · 2025Article
- Electrochemical cyclization of alkynes to construct five-membered nitrogen-heterocyclic rings.Beilstein journal of organic chemistry · 2025Review
- Three-Component Gold(I)-Catalyzed Alkoxyvinylation.Organic letters · 2024Article
- Green advancements towards the electrochemical synthesis of heterocycles.RSC advances · 2024Review
- Electrochemical Late-Stage Functionalization.Chemical reviews · 2023Review
- Sulfoximine Assisted C-H Activation and Annulation via Vinylene Transfer: Access to Unsubstituted Benzothiazines.Molecules (Basel, Switzerland) · 2023Article
- Cobalt-catalyzed radical-mediated carbon-carbon scissionChemical science · 2023Article
- Heterocyclic Electrochemistry: Renewable Electricity in the Construction of Heterocycles.ACS omega · 2023Review
- Silver-Free C-H Activation: Strategic Approaches towards Realizing the Full Potential of C-H Activation in Sustainable Organic Synthesis.Angewandte Chemie (International ed. in English) · 2022Review
- Cu-catalyzed carboboration of acetylene with Michael acceptors.Chemical science · 2022Article
- Distal Ruthenaelectro-Catalyzed meta-C-H Bromination with Aqueous HBr.Angewandte Chemie (International ed. in English) · 2022Article
- Diverse synthesis of C2-linked functionalized molecules via molecular glue strategy with acetylene.Nature communications · 2022Article
- Advances on the Merger of Electrochemistry and Transition Metal Catalysis for Organic Synthesis.Chemical reviews · 2022Review
- Electrochemical organic reactions: A tutorial review.Frontiers in chemistry · 2022Review
- Transition metal-catalyzed organic reactions in undivided electrochemical cells.Chemical science · 2021Review
- Palladium-Catalyzed Cascade Carbonylation to α,β-Unsaturated Piperidones via Selective Cleavage of Carbon-Carbon Triple Bonds.Angewandte Chemie (International ed. in English) · 2021Article
- Vinyl Thianthrenium Tetrafluoroborate: A Practical and Versatile Vinylating Reagent Made from Ethylene.Journal of the American Chemical Society · 2021Article
- Electrocatalysis as an enabling technology for organic synthesis.Chemical Society reviews · 2021Article
- Organic Electrochemistry: Molecular Syntheses with Potential.ACS central science · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethylene and ethyne are among the simplest two-carbon building blocks. However, quite limited methods can be applied to incorporate ethylene or ethyne into fine chemicals. Here we demonstrate a cobalt-catalyzed dehydrogenative C-H/N-H [4+2] annulation of aryl/vinyl amides with ethylene or ethyne by using an electrochemical reaction protocol. Significantly, this work shows an example of electrochemical recycling of cobalt catalyst in oxidative C-H functionalization reactions, avoiding the use of external chemical oxidants and co-oxidants. The electrochemical method provides a reliable and safe way for incorporating gas-phase ethylene or ethyne into fine chemicals. High reaction efficiency and good functional group tolerance are observed under divided electrolytic conditions.
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Registered trials
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