Evidence map›Paper›PMID 29476024›Full record

ArticleG3 (Bethesda, Md.)2018

Targeted Long-Read Sequencing of a Locus Under Long-Term Balancing Selection in

Jörg A Bachmann, Andrew Tedder, Benjamin Laenen, Kim A Steige, Tanja Slotte

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Genome ofProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jörg A BachmannDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Sweden jorg.bachmann@su.se.
Andrew TedderDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Sweden.
Benjamin LaenenDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Sweden.
Kim A SteigeDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Sweden.
Tanja SlotteDepartment of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid advances in short-read DNA sequencing technologies have revolutionized population genomic studies, but there are genomic regions where this technology reaches its limits. Limitations mostly arise due to the difficulties in assembly or alignment to genomic regions of high sequence divergence and high repeat content, which are typical characteristics for loci under strong long-term balancing selection. Studying genetic diversity at such loci therefore remains challenging. Here, we investigate the feasibility and error rates associated with targeted long-read sequencing of a locus under balancing selection. For this purpose, we generated bacterial artificial chromosomes (BACs) containing the Brassicaceae

Indexed as

Genetic LociBase SequenceCapsellaCosts and Cost AnalysisFeasibility StudiesHigh-Throughput Nucleotide SequencingMolecular Sequence Annotationassemblybacterial artificial chromosomesBrassicaceaeCapsellaself-incompatibility locussequencing errorssingle-molecule real-time sequencing

Identifiers

PMID29476024
PMCPMC5873921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.