Evidence map›Paper›PMID 29475860›Full record

ArticleApplied and environmental microbiology2018

Microbiota-Mediated Modulation of Organophosphate Insecticide Toxicity by Species-Dependent Interactions with Lactobacilli in a Drosophila melanogaster Insect Model.

Brendan A Daisley, Mark Trinder, Tim W McDowell, Stephanie L Collins, Mark W Sumarah, Gregor Reid

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 91 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Is it time to assignApplied and environmental microbiology · 2025
    Article
  5. Microbiome evolution plays a secondary role in host rapid adaptation.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Mosquito Gut Microbiota: A Review.Pathogens (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Article
  11. Diversity analyses of bacterial symbionts in fourFrontiers in cellular and infection microbiology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brendan A Daisley *Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada.ORCID 0000-0001-5999-5792
Mark Trinder *Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada.ORCID 0000-0001-8447-2897
Tim W McDowellLondon Research and Development Center, Agriculture and Agri-Food Canada, London, Ontario, Canada.
Stephanie L CollinsCentre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada.ORCID 0000-0002-2773-646X
Mark W SumarahLondon Research and Development Center, Agriculture and Agri-Food Canada, London, Ontario, Canada.ORCID 0000-0003-0977-1656
Gregor ReidCentre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada gregor@uwo.ca.ORCID 0000-0001-9658-5696
Western University · CAAgriculture and Agri-Food Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the benefits to the global food supply and agricultural economies, pesticides are believed to pose a threat to the health of both humans and wildlife. Chlorpyrifos (CP), a commonly used organophosphate insecticide, has poor target specificity and causes acute neurotoxicity in a wide range of species via the suppression of acetylcholinesterase. This effect is exacerbated 10- to 100-fold by chlorpyrifos oxon (CPO), a principal metabolite of CP. Since many animal-associated symbiont microorganisms are known to hydrolyze CP into CPO, we used a

Indexed as

MicrobiotaAnimalsBacteriaChlorpyrifosDrosophila melanogasterInsecticidesLactobacillusModels, AnimalProbioticsSpecies SpecificityChlorpyrifosInsecticidesbiopesticidescolony collapse disorderdetoxificationenvironmental toxinshoney beeslactobacillusmicrobiotapesticidesprobioticsxenobiotics

Identifiers

PMID29475860
PMCPMC5930343
OpenAlexW2789904388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.