ArticleOccupational and environmental medicine2018
Association of hand and arm disinfection with asthma control in US nurses.
Article in Occupational and environmental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Work-Related Asthma and Its Impact on Quality of Life and Work Productivity.The journal of allergy and clinical immunology. In practice · 2024Article
- Exposure to Disinfectants and Cleaning Products and Respiratory Health of Workers and Children in Daycares: The CRESPI Cohort Protocol.International journal of environmental research and public health · 2023Article
- Characterization of Exposure to Cleaning Agents Among Health Workers in Two Southern African Tertiary Hospitals.Annals of work exposures and health · 2022Article
- Residential Exposure to Dampness Is Related to Reduced Level of Asthma Control among Adults.International journal of environmental research and public health · 2022Article
- Cleaning Products and Work-Related Asthma, 10 Year Update.Journal of occupational and environmental medicine · 2020Article
- Occupational exposure to disinfectants and asthma incidence in U.S. nurses: A prospective cohort study.American journal of industrial medicine · 2020Article
- Association of Occupational Exposure to Disinfectants With Incidence of Chronic Obstructive Pulmonary Disease Among US Female Nurses.JAMA network open · 2019Article
- Asthma associated with denatonium benzoate in a healthcare worker in Taiwan: A case report.Medicine · 2019Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
objectivesTo investigate the association between occupational exposure to disinfectants/antiseptics used for hand hygiene and asthma control in nurses.
methodsIn 2014, we invited female nurses with asthma drawn from the Nurses' Health Study II to complete two supplemental questionnaires on their occupation and asthma (cross-sectional study, response rate: 80%). Among 4055 nurses (mean age: 59 years) with physician-diagnosed asthma and asthma medication use in the past year, we examined asthma control, as defined by the Asthma Control Test (ACT). Nurses were asked about the daily frequency of hand hygiene tasks: 'wash/scrub hands with disinfectants/hand sanitizers' (hand hygiene) and 'wash/scrub arms with disinfecting products' (surrogate of surgical hand/arm antisepsis). Analyses were adjusted for age, race, ethnicity, smoking status and body mass index.
resultsNurses with partly controlled asthma (ACT: 20-24, 50%) and poorly controlled asthma (ACT ≤19, 18%) were compared with nurses with controlled asthma (ACT=25, 32%). In separate models, both hand and arm hygiene were associated with poorly controlled asthma. After mutual adjustment, only arm hygiene was associated with poorly controlled asthma: OR (95% CI) for <1 time/day, 1.38 (1.06 to 1.80); ≥1 time/day, 1.96 (1.52 to 2.51), versus never. We observed a consistent dose-response relationship between frequency of arm hygiene tasks (never to >10 times/day) and poor asthma control. Associations persisted after further adjustment for surfaces/instruments disinfection tasks.
conclusionsFrequency of hand/arm hygiene tasks in nurses was associated with poor asthma control. The results suggest an adverse effect of products used for surgical hand/arm antisepsis. This potential new occupational risk factor for asthma warrants further study.
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