Evidence map›Paper›PMID 29475554›Full record

Trial reportJournal of the American Dental Association (1939)2018

Influence of 2 caries-detecting devices on clinical decision making and lesion depth for suspicious occlusal lesions: A randomized trial from The National Dental Practice-Based Research Network.

Sonia K Makhija, James D Bader, Daniel A Shugars, Mark S Litaker, Sanket Nagarkar, Valeria V Gordan, D Brad Rindal, Daniel J Pihlstrom, Rahma Mungia, Cyril Meyerowitz and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Dental Association (1939), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06051981 (The Effect of Fluoride Varnish, Casein Phosphopeptide-Amorphous Calcium Phosphate, and Resin Infiltration in the Treatment of White Spot Lesions After Orthodontic Therapy), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06051981 phase4unknown statusnot on this mapstarted 2023, after this paper: background citation

The Effect of Fluoride Varnish, Casein Phosphopeptide-Amorphous Calcium Phosphate, and Resin Infiltration in the Treatment of White Spot Lesions After Orthodontic Therapy: A Randomized Controlled Trial

TypeinterventionalSponsorRiyadh Elm UniversityRan2023 to 2024Enrolled88ConditionsWhite Spot LesionArms5% sodium fluoride, Intensive 5% sodium fluoride, Casein Phosphopeptide-Amorphous Calcium Phosphate, Resin infiltration
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Dental Caries and Its Management.International journal of dentistry · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sonia K Makhija
James D Bader
Daniel A Shugars
Mark S Litaker
Sanket Nagarkar
Valeria V Gordan
D Brad Rindal
Daniel J Pihlstrom
Rahma Mungia
Cyril Meyerowitz
Gregg H Gilbert
National Dental Practice-Based Research Network (PBRN) Collaborative Group

Funding

The National Dental PBRNU19DE022516 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2012 to 2018
$66.4M
Dental PBRN Network ChairU01DE016747 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2005 to 2011
$17.3M
NIDCR NIH HHS U01 DE016747NIDCR NIH HHS U19 DE022516
6 · The paper itself

Abstract

backgroundA suspicious occlusal carious lesion (SOCL) can be defined as a lesion with no cavitation and no radiographic radiolucency but for which caries is suspected. The authors evaluated whether using a device changed the percentage of SOCLs that were opened surgically and, among those SOCLs that were opened, the proportion that had penetrated into dentin.

methodsEighty-two dentists participated. In phase 1 of the study, dentists identified approximately 20 SOCLs, obtained patient consent, and recorded information about the lesion, treatment or treatments, and depth, if opened. Dentists were then randomly assigned into 1 of 3 groups: no device, DIAGNOdent (KaVo), and Spectra (Air Techniques). In phase 2, dentists enrolled approximately 20 additional patients and recorded the same phase 1 information while using the assigned device to help make their treatment decisions. A mixed-model logistic regression was used to determine any differences after randomization in the proportion of lesions opened and, if opened, the proportion of lesions that penetrated into dentin.

resultsA total of 1,500 SOCLs were enrolled in each phase. No statistically significant difference was found in the change in proportion of lesions receiving invasive treatment from phase 1 to phase 2 across the 3 groups (P = .33) or in the change in proportion of percentage of opened lesions that extended into dentin (P = .31).

conclusionCaries-detecting devices in the study did not change substantially dentists' decisions to intervene or the accuracy of the intervention decision in predicting lesion penetration into dentin. PRACTICAL IMPLICATIONS: The caries-detecting devices tested may not improve dentists' clinical decision making for SOCLs.

Indexed as

Dental CariesDental Restoration, PermanentClinical Decision-MakingDecision MakingDental EnamelDentinHumansPractice Patterns, Dentists'cariesdentinEvidence-based dentistry

Identifiers

PMID29475554
PMCPMC5878106

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.