Evidence map›Paper›PMID 29475460›Full record

ArticleThe Kaohsiung journal of medical sciences2018

Brain-derived neurotrophic factor preserves intestinal mucosal barrier function and alters gut microbiota in mice.

Chen Li, Yong-Yan Cai, Zhi-Xin Yan

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 58 citations in OpenAlex.

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  10. Heliyon · 2024
    Article
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  15. The Role of the Gut Microbiome in Diet and Exercise Effects on Cognition: A Review of the Intervention Literature.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
  16. Annals of medicine · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chen LiThe Fifth Department of Pediatrics Medicine, Cangzhou Central Hospital, Cangzhou, PR China.
Yong-Yan CaiThe First Department of Pediatrics Medicine, Cangzhou Central Hospital, Cangzhou, PR China. Electronic address: caiyy0816@163.com.
Zhi-Xin YanThe First Department of Pediatrics Medicine, Cangzhou Central Hospital, Cangzhou, PR China.
Cangzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal mucosal barrier (IMB) enables the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. In this study, we explored the effect of brain-derived neurotrophic factor (BDNF) on IMB function and gut microbiota in mice. BDNF gene knock-out mice (the BDNF

Indexed as

AnimalsBrain-Derived Neurotrophic FactorClaudin-1Claudin-2ColonGastrointestinal MicrobiomeGene Expression RegulationIleumIntestinal MucosaMaleMiceMice, KnockoutMicrovilliOccludinTight JunctionsZonula Occludens-1 ProteinBrain-Derived Neurotrophic FactorClaudin-1Claudin-2OccludinOcln protein, mouseTjp1 protein, mouseZonula Occludens-1 ProteinBrain-derived neurotrophic factorGut microbiotaIntestinal mucosal barrier functionOccludinZO-1

Identifiers

PMID29475460
PMCPMC11915681
OpenAlexW2790723460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.