Evidence map›Paper›PMID 29475243›Full record

ArticlePsychiatry investigation2018

The Impact of General Medical Conditions in Obsessive-Compulsive Disorder.

Andrea Aguglia, Maria Salvina Signorelli, Umberto Albert, Giuseppe Maina

Abstract read
In one paragraph

Article in Psychiatry investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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  16. Article
  17. Propensity to Sexual Response among Adults with Obsessive-Compulsive Disorder.Clinical practice and epidemiology in mental health : CP & EMH · 2019
    Article
  18. Review
  19. Obsessive-Compulsive Disorder: A Medical School Curriculum and Textbook Review.Journal of medical education and curricular development
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea Aguglia"Rita Levi Montalcini" Department of Neuroscience, University of Turin, Psychiatric Unit, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.
Maria Salvina SignorelliDepartment of Clinical and Experimental Medicine, AOU Policlinico Hospital, University of Catania, Catania, Italy.
Umberto Albert"Rita Levi Montalcini" Department of Neuroscience, University of Turin, Psychiatric Unit, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.
Giuseppe Maina"Rita Levi Montalcini" Department of Neuroscience, University of Turin, Psychiatric Unit, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe co-occurrence of general medical conditions (GMCs) and major psychiatric disorders is well documented. The aim of this study was to assess the prevalence of GMCs in patients with a primary diagnosis of obsessive-compulsive disorder (OCD) and, secondly, to investigate which clinical variables are associated with the presence of a GMC.

methodsSubjects with a primary diagnosis of OCD were included. Socio-demographic and clinical characteristics were collected. GMCs were classified using the ICD-10 and grouped according to the Cumulative Illness Rating Scale (CIRS) in: cardiac, vascular, hematopoietic, respiratory, ear/nose/throat, upper and lower gastrointestinal, hepatic, renal, genitourinary, musculoskeletal, neurologic, endocrine/metabolic. The association between the presence of GMCs and demographic/clinical variables of OCD was investigated.

resultsA total of 162 patients with OCD were included. 78 (48.1%) patients had at least one comorbid GMC. Most frequent GMCs were endocrine/metabolic diseases (25.9%), followed by upper/lower gastrointestinal (20.5%) and cardio-vascular diseases (13.6%). The presence of a GMC was significantly associated with female gender, older age, duration of untreated illness (DUI), and absence of physical activity.

conclusionPatients with OCD have high rates of comorbid GMCs. A longer DUI is associated with having at least one GMCs; this might be due to the long-lasting adoption of unhealthy lifestyles, not counterbalanced by appropriate treatment and psychoeducation.

Indexed as

Cardiovascular diseaseDuration of untreated illnessGeneral medical conditionMedical illnessObsessive-compulsive disorder

Identifiers

PMID29475243
PMCPMC5900370

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.