Evidence map›Paper›PMID 29474713›Full record

SynthesisEuropean heart journal. Quality of care & clinical outcomes2016

The role of mHealth for improving medication adherence in patients with cardiovascular disease: a systematic review.

Yousuf Gandapur, Sina Kianoush, Heval M Kelli, Satish Misra, Bruno Urrea, Michael J Blaha, Garth Graham, Francoise A Marvel, Seth S Martin

4 registry-linked trialsOpen access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European heart journal. Quality of care & clinical outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 103 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 8 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03728790 nacompletednot on this mapstarted 2018, after this paper: background citation

A Remote Postpartum (PP) Blood Pressure Surveillance and Reminder System for Hypertensive Disorders of Pregnancy: A Randomized Clinical Trial

TypeinterventionalSponsorColumbia UniversityRan2018 to 2020Enrolled213ConditionsHypertensive Disorder of PregnancyArmsRemote Patient Monitoring
NCT04577157 nacompletednot on this mapstarted 2021, after this paper: background citation

Effectiveness of mHealth Intervention Using Multifaceted Educational and Reminder Module Intervention to Improve Medication Adherence and Treatment Outcome Among Hypertensive Patients in Lahore, Pakistan: a Randomized Controlled Trial

TypeinterventionalSponsorUniversiti Putra MalaysiaRan2021 to 2021Enrolled440ConditionsMedication Adherence, Adherence, TreatmentArmsmHealth using"WhatsApp" multifaceted educational and reminder module intervention to improve adherence
NCT05622292 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effectivity of the Mobile App "HARKIT I-Care" in Secondary Prevention in Post Acute Coronary Syndrome Patients in National Cardiovascular Center Harapan Kita Hospital

TypeinterventionalSponsorNational Cardiovascular Center Harapan Kita Hospital IndonesiaRan2022 to 2023Enrolled60ConditionsAcute Coronary SyndromeArmsHARKIT I-Care Application
NCT06108674 narecruitingnot on this mapstarted 2023, after this paper: background citation

Evaluation of the Effectiveness of Telepharmacy on Clinical Outcomes of Patients With Arterial Hypertension: Celeste Randomized Clinical Trial

TypeinterventionalSponsorFederal University of BahiaRan2023 to 2026Enrolled194ConditionsHypertensionArmsPharmaceutical care via telepharmacy and usual care, Pharmaceutical care in-person and usual care
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 8 syntheses or guidelines pooled it, 209 citations in OpenAlex.

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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yousuf GandapurDepartment of Internal Medicine, Good Samaritan/Union Memorial Hospital, 201 East University Parkway, Baltimore, MD 21218, USA.
Sina KianoushCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Heval M KelliEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA, USA.
Satish MisraCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bruno UrreaCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Michael J BlahaCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Garth GrahamAetna Foundation, Hartford, CT, USA.
Francoise A MarvelCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Seth S MartinCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins Medicine · USJohns Hopkins University · USAetna Foundation · USEmory Clinic · USMedStar Union Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is a leading cause of morbidity and mortality worldwide, and a key barrier to improved outcomes is medication non-adherence. The aim of this study is to review the role of mobile health (mHealth) tools for improving medication adherence in patients with cardiovascular disease. We performed a systematic search for randomized controlled trials that primarily investigated mHealth tools for improving adherence to cardiovascular disease medications in patients with hypertension, coronary artery disease, heart failure, peripheral arterial disease, and stroke. We extracted and reviewed data on the types of mHealth tools used, preferences of patients and healthcare providers, the effect of the mHealth interventions on medication adherence, and the limitations of trials. We identified 10 completed trials matching our selection criteria, mostly with <100 participants, and ranging in duration from 1 to 18 months. mHealth tools included text messages, Bluetooth-enabled electronic pill boxes, online messaging platforms, and interactive voice calls. Patients and healthcare providers generally preferred mHealth to other interventions. All 10 studies reported that mHealth interventions improved medication adherence, though the magnitude of benefit was not consistently large and in one study was not greater than a telehealth comparator. Limitations of trials included small sample sizes, short duration of follow-up, self-reported outcomes, and insufficient assessment of unintended harms and financial implications. Current evidence suggests that mHealth tools can improve medication adherence in patients with cardiovascular diseases. However, high-quality clinical trials of sufficient size and duration are needed to move the field forward and justify use in routine care.

Indexed as

Drug MonitoringAdultAgedAged, 80 and overCardiovascular DiseasesCell PhoneCoronary Artery DiseaseFemaleHeart FailureHumansHypertensionMaleMiddle AgedOutcome Assessment, Health CarePeripheral Arterial DiseaseRandomized Controlled Trials as Topic

Identifiers

PMID29474713
PMCPMC5862021
OpenAlexW2342277966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.