ArticlePLoS pathogens2018
Insect tissue-specific vitellogenin facilitates transmission of plant virus.
Article in PLoS pathogens, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 71 citations in OpenAlex.
- Transient Expression of Bta78 Gene in Nicotiana benthamiana Enhances Whitefly Feeding Activity.Archives of insect biochemistry and physiology · 2026Article
- Dual functions of the Aedes aegypti ecdysone receptor in dengue virus replication and reproduction control.Parasites & vectors · 2026Article
- Rice stripe virus utilizes aeLife · 2026Article
- Macrophage-mediated nutrient recycling: evolutionary insights into the metabolic role of professional phagocytes.Frontiers in immunology · 2026Review
- A plant virus attenuates the Toll immune pathway by degradation of Pellino to facilitate viral infection in insect vectors.Journal of virology · 2025Article
- Chitin Deacetylase Gene Family Positively Regulates the Accumulation of Rice Stripe Virus inInsects · 2025Article
- Review
- Proteomic analysis unveils host-parasite interactions in Aedes togoi infected with Dirofilaria immitis and Brugia pahangi.PloS one · 2025Article
- The low-density lipoprotein receptor and apolipoprotein E associated with CCHFV particles mediate CCHFV entry into cells.Nature communications · 2024Article
- Genome-Wide Identification of Vitellogenin Gene Family and Comparative Analysis of Their Involvement in Ovarian Maturation inInternational journal of molecular sciences · 2024Article
- Transcriptional signature of host shift in the seed beetle Zabrotes subfasciatus.Genetics and molecular biology · 2024Article
- Microsporidian Nosema bombycis hijacks host vitellogenin and restructures ovariole cells for transovarial transmission.PLoS pathogens · 2023Article
- Review
- Interaction between the flagellum ofFrontiers in microbiology · 2023Article
- MiR-2b-2-5p regulates lipid metabolism and reproduction by targetingRNA biology · 2023Article
- Molecular Characterization of Vitellogenin and Its Receptor inInternational journal of molecular sciences · 2022Article
- Interaction of Liberibacter Solanacearum with Host Psyllid Vitellogenin and Its Association with Autophagy.Microbiology spectrum · 2022Article
- GrpE is involved in mitochondrial function and is an effective target for RNAi-mediated pest and arbovirus control.Insect molecular biology · 2022Article
- Vitellogenin-2 Accumulation in the Fat Body and Hemolymph ofFrontiers in cellular and infection microbiology · 2022Article
- Comparative transcriptome profiling reveals a network of differentially expressed genes in Asia II 7 and MEAM1 whitefly cryptic species in response to early infection ofFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insect vitellogenin (Vg) has been considered to be synthesized in the fat body. Here, we found that abundant Vg protein is synthesized in Laodelphax striatellus hemocytes as well. We also determined that only the hemocyte-produced Vg binds to Rice stripe virus (RSV) in vivo. Examination of the subunit composition of L. striatellus Vg (LsVg) revealed that LsVg was processed differently after its expression in different tissues. The LsVg subunit able to bind to RSV exist stably only in hemocytes, while fat body-produced LsVg lacks the RSV-interacting subunit. Nymph and male L. striatellus individuals also synthesize Vg but only in hemocytes, and the proteins co-localize with RSV. We observed that knockdown of LsVg transcripts by RNA interference decreased the RSV titer in the hemolymph, and thus interfered with systemic virus infection. Our results reveal the sex-independent expression and tissue-specific processing of LsVg and also unprecedentedly connect the function of this protein in mediating virus transmission to its particular molecular forms existing in tissues previously known as non-Vg producing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.