Evidence map›Paper›PMID 29474119›Full record

ArticleSubstance abuse2018

Description and outcomes of a buprenorphine maintenance treatment program integrated within Prevention Point Philadelphia, an urban syringe exchange program.

Marcus A Bachhuber, Cole Thompson, Ann Prybylowski, José Benitez, Silvana Mazzella, David Barclay

Open access · greenAbstract read
In one paragraph

Article in Substance abuse, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

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  7. A call for upstream solutions to the unregulated drug crisis in British Columbia, Canada: Locked up or locked out.Canadian journal of public health = Revue canadienne de sante publique · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marcus A Bachhubera Division of General Internal Medicine, Department of Medicine , Montefiore Medical Center/Albert Einstein College of Medicine , Bronx , New York , USA.
Cole Thompsonb Perelman School of Medicine at the University of Pennsylvania , Philadelphia , Pennsylvania , USA.
Ann Prybylowskib Perelman School of Medicine at the University of Pennsylvania , Philadelphia , Pennsylvania , USA.
José Benitezc Prevention Point Philadelphia , Philadelphia , Pennsylvania , USA.
Silvana Mazzellac Prevention Point Philadelphia , Philadelphia , Pennsylvania , USA.
David Barclayc Prevention Point Philadelphia , Philadelphia , Pennsylvania , USA.
Center Point · USUniversity of Pennsylvania · USAlbert Einstein College of Medicine · US

Funding

NIMHD NIH HHS L60 MD010933
6 · The paper itself

Abstract

backgroundSyringe exchange programs are uniquely positioned to offer treatment services to interested clients. Prevention Point Philadelphia recently expanded to offer buprenorphine maintenance treatment through its Stabilization, Treatment, and Engagement Program (STEP).

objectiveTo describe the STEP model of care and report treatment outcomes.

methodsRetrospective chart review of patients enrolled in STEP (October 2011-August 2014). Our main outcome measure was time retained in treatment, defined as time from treatment initiation to treatment failure. Secondary outcome measures were buprenorphine and opiate use, from urine toxicology screens. We analyzed retention in treatment using Kaplan-Meier survival estimates; patients who remained in treatment at the end of the study period were censored on that day. For buprenorphine and opiate use, we calculated the percentage of patients who were positive for buprenorphine and opiates in each month of treatment.

resultsOf the 124 patients enrolled in STEP, the median age was 41 (range 21 to 63) and 80% reported injection heroin use. Comorbidities were common: 33% had HIV infection, most reported anxiety (78%) or depression (71%), and 20% were homeless. The most common program outcomes were unplanned self-discharge (n = 29; 23%), incarceration (n = 20; 16%), and administrative discharge (n = 19; 15%). The percentage of patients retained in treatment at 3, 6, 9, and 12 months was 77%, 65%, 59%, and 56%, respectively. Among those retained, the percentage with a positive buprenorphine screen at 3, 6, 9, and 12 months was 88%, 100%, 96%, and 95%, respectively. The percentage with a positive opiates screen was 19%, 13%, 17%, and 16%, respectively.

conclusionsWith a program that blended organizational and community resources, retention in buprenorphine maintenance treatment was comparable to retention rates reported from other settings. Further research should directly compare treatment outcomes in syringe exchange program-based settings versus primary care and specialty settings.

Indexed as

Needle-Exchange ProgramsProgram DevelopmentAdultBuprenorphineFemaleHumansMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient CompliancePhiladelphiaRetrospective StudiesTreatment OutcomeUrban PopulationYoung AdultBuprenorphinebuprenorphinedrug usersheroinheroin dependenceopioid-related disorderssyringe-exchange programs

Identifiers

PMID29474119
PMCPMC9333078
OpenAlexW2790101060

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.