Evidence map›Paper›PMID 29473904›Full record

ArticleInternational journal of molecular sciences2018

Sinus Bradycardia in Carriers of the SCN5A-1795insD Mutation: Unraveling the Mechanism through Computer Simulations.

Ronald Wilders

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Long QT Syndrome and Sinus Bradycardia-A Mini Review.Frontiers in cardiovascular medicine · 2018
    Review
  6. Disease Modifiers of InheritedFrontiers in cardiovascular medicine · 2018
    Review
  7. Frontiers in physiology · 2018
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ronald WildersDepartment of Medical Biology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands. r.wilders@amc.uva.nl.ORCID 0000-0002-1340-0869
Amsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Computer SimulationAction PotentialsBradycardiaHeart RateHeterozygoteHumansIon Channel GatingMutationNAV1.5 Voltage-Gated Sodium ChannelSinoatrial NodeNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, humancomputer simulationselectrophysiologygeneticsheartion channelslong-QT syndromesick sinus syndromesinoatrial nodesinus bradycardiasodium current

Identifiers

PMID29473904
PMCPMC5855856
OpenAlexW2792584703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.