Evidence map›Paper›PMID 29473886›Full record

ArticleMolecules (Basel, Switzerland)2018

Antioxidation and Cytoprotection of Acteoside and Its Derivatives: Comparison and Mechanistic Chemistry.

Xican Li, Yulu Xie, Ke Li, Aizhi Wu, Hong Xie, Qian Guo, Penghui Xue, Yerkingul Maleshibek, Wei Zhao, Jiasong Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. The extract ofPharmaceutical biology · 2025
    Article
  7. Chemical Constituents and Anticancer Activities of the Extracts fromInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Acteoside Counteracts Interleukin-1Oxidative medicine and cellular longevity · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Antioxidant Mechanisms of Echinatin and Licochalcone A.Molecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xican LiSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. lixc@gzucm.edu.cn.ORCID 0000-0002-4358-3993
Yulu XieSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. xieyulu1900@163.com.
Ke LiSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. ys1090992678@163.com.
Aizhi WuSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. lixican@126.com.ORCID 0000-0002-4358-3993
Hong XieSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. xiehongxh1@163.com.
Qian GuoSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. 15622178307@163.com.
Penghui XueSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. 15228738137@163.com.
Yerkingul MaleshibekSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. pandiphd@163.com.
Wei ZhaoZhongshan School of Medicine, Sun Yat-sen University, No. 74 Zhongshan Road. 2, Guangzhou 510080, China. zhaowei23@mail.sysu.edu.cn.
Jiasong GuoDepartment of Histology and Embryology, Southern Medical University, Guangzhou 510515, China. jiasongguo@aliyun.com.
Dongfeng ChenSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. chen888@gzucm.edu.cn.
Guangzhou University of Chinese Medicine · CNSouthern Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study tried to explore the role of sugar-residues and mechanisms of phenolic phenylpropanoid antioxidants. Acteoside, along with its apioside forsythoside B and rhamnoside poliumoside, were comparatively investigated using various antioxidant assays. In three electron-transfer (ET)-based assays (FRAP, CUPRAC, PTIO•-scavenging at pH 4.5), the relative antioxidant levels roughly ruled as: acteoside >forsythoside B > poliumoside. Such order was also observed in H⁺-transfer-involved PTIO•-scavenging assay at pH 7.4, and in three multiple-pathway-involved radical-scavenging assays, i.e., ABTS⁺•-scavenging, DPPH•-scavenging, and •O₂

Indexed as

CytoprotectionAntioxidantsFree Radical ScavengersGlucosidesIron Chelating AgentsMechanical PhenomenaMetalsMolecular StructurePhenolsPolyphenolsSpectrometry, Mass, Electrospray IonizationSpectrophotometry, UltravioletTandem Mass SpectrometryacteosideAntioxidantsFree Radical ScavengersGlucosidesIron Chelating AgentsMetalsPhenolsPolyphenolsacteosideapiosylforsythoside Bphenylpropanoid glycosidespoliumosiderhamnosyl

Identifiers

PMID29473886
PMCPMC6017589
OpenAlexW2794257582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.