Evidence map›Paper›PMID 29473846›Full record

ArticleInternational journal of molecular sciences2018

Epigallocatechin Gallate Reduces Ischemia/Reperfusion Injury in Isolated Perfused Rabbit Hearts.

Aida Salameh, Roxana Schuster, Ingo Dähnert, Johannes Seeger, Stefan Dhein

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aida SalamehHeart Centre Clinic for Paediatric Cardiology, University of Leipzig, 04289 Leipzig, Germany. aida.salameh@medizin.uni-leipzig.de.
Roxana SchusterHeart Centre Clinic for Paediatric Cardiology, University of Leipzig, 04289 Leipzig, Germany. roxanaschuster@gmx.de.
Ingo DähnertHeart Centre Clinic for Paediatric Cardiology, University of Leipzig, 04289 Leipzig, Germany. ingo.daehnert@medizin.uni-leipzig.de.
Johannes SeegerInstitute of Veterinary Anatomy, Histology and Embryology, University of Leipzig, 04103 Leipzig, Germany. seeger@vetmed.uni-leipzig.de.
Stefan DheinRudolf-Boehm-Institute for Pharmacology and Toxicology, University of Leipzig, 04107 Leipzig, Germany. stefan.dhein@medizin.uni-leipzig.de.
Leipzig Heart Institute · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardioplegic arrest during heart operations is often used in cardiac surgery. During cardioplegia, the heart is subjected to a global ischemia/reperfusion-injury. (-)-epigallocatechin gallate (EGCG), one of the main ingredients of green tea, seems to be beneficial in various cardiac diseases. Therefore, the aim of our study was to evaluate EGCG in a rabbit model of cardioplegic arrest. Twenty four mature Chinchilla rabbits were examined. Rabbit hearts were isolated and perfused according to Langendorff. After induction of cardioplegia (without and with 20 µmol/L EGCG,

Indexed as

PerfusionAnimalsApoptosis Inducing FactorBlood PressureCatechinHeartHeart VentriclesHemodynamicsHypoxia-Inducible Factor 1, alpha SubunitMyocardial ContractionMyocardial Reperfusion InjuryRabbitsStaining and LabelingApoptosis Inducing FactorCatechinepigallocatechin gallateHypoxia-Inducible Factor 1, alpha SubunitcardioplegiaEGCGischemia/reperfusion injuryLangendorff

Identifiers

PMID29473846
PMCPMC5855850
OpenAlexW2792020503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.