Evidence map›Paper›PMID 29473818›Full record

ArticlePhysiological genomics2018

Transcriptomic sequencing reveals diverse adaptive gene expression responses of human vascular smooth muscle cells to nitro-conjugated linoleic acid.

Shengdi Li, Ziyi Chang, Tianqing Zhu, Luis Villacorta, Yixue Li, Bruce A Freeman, Y Eugene Chen, Jifeng Zhang

Abstract read
In one paragraph

Article in Physiological genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Lipoxin AbioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shengdi LiFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.ORCID 0000-0001-8993-3525
Ziyi ChangFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.
Tianqing ZhuFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.
Luis VillacortaFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.
Yixue LiKey Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai , China.
Bruce A FreemanDepartment of Pharmacology and Chemical Biology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Y Eugene ChenFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.
Jifeng ZhangFrankel Cardiovascular Center, Department of Internal Medicine, University of Michigan Medical Center , Ann Arbor, Michigan.

Funding

Vascular Subphenotypes of Lung DiseaseP01HL103455 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLADWIN, MARK T · 2011 to 2020
$26.1M
The Role of PPAR-gamma in Vascular Lesion FormationR01HL068878 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHEN, YUQING EUGENE · 2002 to 2019
$7.6M
KLF14 and Cardiovascular DiseaseR01HL134569 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHEN, YUQING EUGENE · 2017 to 2024
$5.3M
Redox Transduction of Nitric Oxide SignalingR37HL058115 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN · 2008 to 2017
$5.2M
Anti-Inflammatory Lipid Mediators in AsthmaR01HL132550 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN, HOLGUIN, FERNANDO · 2016 to 2019
$2.9M
Kruppel-like factor 11 (KLF11) and atherosclerosisR01HL138139 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZHANG, JIFENG · 2017 to 2021
$2.3M
Conjugated linoleic acid nitration in vascular inflammation and atherosclerosisR01HL123333 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VILLACORTA, LUIS · 2015 to 2019
$2.0M
NHLBI NIH HHS P01 HL103455NHLBI NIH HHS R01 HL068878NHLBI NIH HHS R01 HL123333NHLBI NIH HHS R01 HL132550NHLBI NIH HHS R01 HL134569NHLBI NIH HHS R01 HL138139NHLBI NIH HHS R37 HL058115
6 · The paper itself

Abstract

Nitro-conjugated linoleic acid (NO

Indexed as

Computational BiologyCoronary VesselsGene ExpressionHumansLinoleic Acids, ConjugatedLipid MetabolismMuscle, Smooth, VascularMyocytes, Smooth MuscleSignal TransductionLinoleic Acids, Conjugatedconjugated linoleic acidnitroalkenenitro-fatty acidRNA-Seqvascular smooth muscle cell

Identifiers

PMID29473818
PMCPMC5966802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.