Evidence map›Paper›PMID 29473666›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2018

Validation of a dynamic joint contracture measuring device in a live rabbit model of arthrofibrosis.

Nicolas Reina, William H Trousdale, Christopher G Salib, Loribeth Q Evertz, Lawrence J Berglund, Andre J van Wijnen, Timothy E Hewett, Charlotte E Berry, Daniel J Berry, Mark E Morrey and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. An Abbreviated Rabbit Knee Model of Joint Contracture.Tissue engineering. Part C, Methods · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Biomechanical, histological, and molecular characterization of a new posttraumatic model of arthrofibrosis in rats.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  9. Article
  10. Review
  11. Reduction of arthrofibrosis utilizing a collagen membrane drug-eluting scaffold with celecoxib and subcutaneous injections with ketotifen.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  12. Article
  13. Inhibition of COX-2 Pathway as a Potential Prophylaxis Against Arthrofibrogenesis in a Rabbit Model of Joint Contracture.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Nicolas ReinaDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
William H TrousdaleDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Christopher G SalibDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Loribeth Q EvertzDepartment of Physiology and Biomechanical Engineering, Mayo Clinic, Rochester, Minnesota, 55905.
Lawrence J BerglundDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Andre J van WijnenDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Timothy E HewettDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Charlotte E BerryDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Daniel J BerryDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Mark E MorreyDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Joaquin Sanchez-SoteloDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Matthew P AbdelDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

Pathologic Role of Inflammation and Mechanistic Analysis of Myofibroblastogenesis in ArthrofibrosisR01AR072597 · NIAMS · MAYO CLINIC ROCHESTER · PI ABDEL, MATTHEW P · 2018 to 2022
$1.7M
NIAMS NIH HHS R01 AR072597
6 · The paper itself

Abstract

The current method of measuring arthrofibrosis in live rabbits is critically limited. Specifically, this method involves radioactive fluoroscopy, error-prone goniometric measurements, and static joint angle outcomes that fail to approximate the compliance of tissues surrounding the joint. This study aims to validate a novel method of capturing the compliance of contracted tissues surrounding the joint without the use of fluoroscopy or animal sacrifice. Surgically induced contractures of one-hundred and eight rabbits were measured using the current standard of contracture measurement (a pulley system) as well as a newly designed dynamic load cell (DLC) device. The DLC device was highly reliable when compared to the pulley system (r = 0.907, p < 0.001). Finally, the DLC device produced joint stiffness hysteresis curves capable of approximating the compliance of stiff joint tissues, ultimately calculating a mean joint stiffness of 1.57 ± 1.31 N · m · rad

Indexed as

arthrofibrosisjoint contractureknee biomechanicsrabbit model

Identifiers

PMID29473666
PMCPMC8087160
OpenAlexW2793916629

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.