Evidence map›Paper›PMID 29473553›Full record

ArticleNeurology. Clinical practice2014

Microbial DNA testing for inflammatory diseases of the brain of uncertain etiology.

Courtney Takahashi, Michele Mass, Bronwyn Hamilton, Satir Humayun Guletkin, Dennis Bourdette

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Courtney TakahashiDepartments of Neurology (CT, MM, DB), Neuroradiology (BH), and Pathology (SHG), Oregon Health & Science University, Portland; and the VA Multiple Sclerosis Center of Excellence-West (DB), Portland Department of Veterans Affairs Medical Center, OR.
Michele MassDepartments of Neurology (CT, MM, DB), Neuroradiology (BH), and Pathology (SHG), Oregon Health & Science University, Portland; and the VA Multiple Sclerosis Center of Excellence-West (DB), Portland Department of Veterans Affairs Medical Center, OR.
Bronwyn HamiltonDepartments of Neurology (CT, MM, DB), Neuroradiology (BH), and Pathology (SHG), Oregon Health & Science University, Portland; and the VA Multiple Sclerosis Center of Excellence-West (DB), Portland Department of Veterans Affairs Medical Center, OR.
Satir Humayun GuletkinDepartments of Neurology (CT, MM, DB), Neuroradiology (BH), and Pathology (SHG), Oregon Health & Science University, Portland; and the VA Multiple Sclerosis Center of Excellence-West (DB), Portland Department of Veterans Affairs Medical Center, OR.
Dennis BourdetteDepartments of Neurology (CT, MM, DB), Neuroradiology (BH), and Pathology (SHG), Oregon Health & Science University, Portland; and the VA Multiple Sclerosis Center of Excellence-West (DB), Portland Department of Veterans Affairs Medical Center, OR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurologists may be confronted with patients who present with inflammatory brain lesions where the diagnosis cannot be made through history and physical examination alone. Molecular testing for bacterial infections, tuberculosis, and fungal infections may aid in the diagnosis. Since the treatments for these disorders are different and delays can result in permanent neurologic disability and death, rapid and accurate diagnoses are critical. This review provides the neurologist with testing options and recommends ways to enhance sensitivity and specificity.

Identifiers

PMID29473553
PMCPMC5764514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.