ArticleeLife2018
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Hippo signaling regulates cuticle pigmentation and dopamine metabolism in Drosophila.PLoS genetics · 2026Article
- Insect neuropeptides as agents for pest control: potential and challenges.Biological research · 2025Review
- Redox regulation of memory formation by Rrp1 inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Hippo signaling regulates cuticle pigmentation and dopamine metabolism inbioRxiv : the preprint server for biology · 2025Article
- Casomorphine-10 (CM-10) Peptide Orchestrates Circadian and Neurodevelopmental Gene Clusters via δ-Opioid Receptor Signaling: Insights from Transcriptome Analysis with δ-Opioid Receptor-Expressing HEK293 Cells.Life (Basel, Switzerland) · 2025Article
- PKA restricts ERK signaling in learning and memory Kenyon cell neurons.Cellular signalling · 2025Article
- Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila.Biology open · 2024Article
- Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila.bioRxiv : the preprint server for biology · 2024Article
- Use-Dependent, Untapped Dual Kinase Signaling Localized in Brain Learning Circuitry.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Learning and memory using Drosophila melanogaster: a focus on advances made in the fifth decade of research.Genetics · 2023Article
- An optimized temporally controlled Gal4 system inFrontiers in neuroscience · 2023Article
- CREBB repression of protein synthesis in mushroom body gates long-term memory formation inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling.Science advances · 2022Article
- Functional Dissection of Protein Kinases in Sexual Development and Female Receptivity ofFrontiers in cell and developmental biology · 2022Article
- Neuropeptide F inhibits dopamine neuron interference of long-term memory consolidation iniScience · 2021Article
- Memorizing environmental signals through feedback and feedforward loops.Current opinion in cell biology · 2021Review
- An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms.eLife · 2019Article
- Using Nanobodies to Study Protein Function in Developing Organisms.Antibodies (Basel, Switzerland) · 2019Review
- Triacylglycerol Metabolism inGenetics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Pei-Tseng LeeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-7501-7881
Guang LinDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0001-5594-3397
Wen-Wen LinDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Fengqiu DiaoLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.
Benjamin H WhiteLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.ORCID 0000-0003-0612-8075
Hugo J BellenDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0001-5992-5989
Baylor College of Medicine · USNational Institutes of Health · USHoward Hughes Medical Institute · US
Funding
Identifying Neural Substrates of Behavior in Drosophila MelanogasterZIAMH002800 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, BENJAMIN H · 2009 to 2025
$29.2MTransposon induced disruption of most Drosophila genesR01GM067858 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2003 to 2020
$15.7MResource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8MHoward Hughes Medical InstituteNICHD NIH HHS U54 HD083092NICHD NIH HHS U54HD083092NIGMS NIH HHS R01 GM067858NIGMS NIH HHS R01GM067858NIH HHS P40 OD018537
Abstract
In
Indexed as
Memory, Long-TermAnimalsConditioning, ClassicalCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinDrosophilaDrosophila ProteinsGene Knockdown TechniquesGenetic Complementation TestOlfactory PerceptionProtein KinasesTrans-ActivatorsCrebB protein, DrosophilaCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinDrosophila Proteinsmeng protein, DrosophilaProtein KinasesTrans-ActivatorsdeGradFPD. melanogasterDrosophilaMiMICmushroom bodiesneuroscienceSBK1T2A-GAL4
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.