Evidence map›Paper›PMID 29473099›Full record

ReviewApplied microbiology and biotechnology2018

The filamentous fungal pellet-relationship between morphology and productivity.

Lukas Veiter, Vignesh Rajamanickam, Christoph Herwig

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed.

  1. Article
  2. Optimization of fermentation parameters and mutagenesis of Glarea lozoyensis ATCC 20868 towards pneumocandin BBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Extracellular Phosphate Availability ImpactsJournal of fungi (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Morphology-engineered alleviation of mycelial aggregation inSynthetic and systems biotechnology · 2025
    Article
  18. Article
  19. Article
  20. Review

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lukas VeiterResearch Area Biochemical Engineering, Institute of Chemical Engineering, TU Wien, Gumpendorfer Straße 1a, 1060, Vienna, Austria.
Vignesh RajamanickamResearch Area Biochemical Engineering, Institute of Chemical Engineering, TU Wien, Gumpendorfer Straße 1a, 1060, Vienna, Austria.
Christoph HerwigResearch Area Biochemical Engineering, Institute of Chemical Engineering, TU Wien, Gumpendorfer Straße 1a, 1060, Vienna, Austria. christoph.herwig@tuwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filamentous fungi are used for the production of a multitude of highly relevant biotechnological products like citric acid and penicillin. In submerged culture, fungi can either grow in dispersed form or as spherical pellets consisting of aggregated hyphal structures. Pellet morphology, process control and productivity are highly interlinked. On the one hand, process control in a bioreactor usually demands for compact and small pellets due to rheological issues. On the other hand, optimal productivity might be associated with less dense and larger morphology. Over the years, several publications have dealt with aforementioned relations within the confines of specific organisms and products. However, contributions which evaluate such interlinkages across several fungal species are scarce. For this purpose, we are looking into methods to manipulate fungal pellet morphology in relation to individual species and products. This review attempts to address (i) how variability of pellet morphology can be assessed and (ii) how morphology is linked to productivity. Firstly, the mechanism of pellet formation is outlined. Subsequently, the description and analysis of morphological variations are discussed to finally establish interlinkages between productivity, performance and morphology across different fungal species.

Indexed as

BioreactorsBatch Cell Culture TechniquesFungiIndustrial MicrobiologyRheologyAnalysis of morphologyFungal pellet morphologyInterlinks between productivity and morphologyVariability and alteration of morphology

Identifiers

PMID29473099
PMCPMC5852183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.