ReviewAbdominal radiology (New York)2018
Assessment of iodine uptake by pancreatic cancer following chemotherapy using dual-energy CT.
Review in Abdominal radiology (New York), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Practical applications of photon-counting CT in oncology: an organ-based pictorial review.Insights into imaging · 2026Article
- Targeting Reactive Species Stress and Nutrient Sensing to Enhance NK-Cell Function: Mechanistic Strategies for Overcoming Pancreatic Cancer Progression and Resistance Through Supplement Therapy.International journal of molecular sciences · 2026Review
- Impact of image reconstruction algorithms on histogram analysis of iodine concentration for assessing chemotherapy response in pancreatic ductal adenocarcinoma.Abdominal radiology (New York) · 2026Article
- Seeing the invisible: practical strategies to maximize the clinical impact of photon-counting CT in abdominal imaging.Abdominal radiology (New York) · 2026Review
- Phantom-derived method for improving accurate material decomposition in photon-counting detector CT.European radiology experimental · 2026Article
- Revolution APEX CT: preliminary assessment of its application value in pancreatic cancer T staging.BMC medical imaging · 2026Article
- Beyond Conventional CT: Role of Dual-Energy CT in Monitoring Response to Therapy in Abdominal Malignancies.Radiology. Imaging cancer · 2025Review
- Benefits of Dual-Layer Spectral CT Imaging in Staging and Preoperative Evaluation of Pancreatic Ductal Adenocarcinoma.Journal of clinical medicine · 2023Article
- Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Article
- Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma: Role of the Radiologist and Oncologist in the Era of Precision Medicine.Diagnostics (Basel, Switzerland) · 2021Review
- Dual Energy Differential Phase Contrast CT (DE-DPC-CT) Imaging.IEEE transactions on medical imaging · 2020Article
- Pancreatic Ductal Adenocarcinoma: Interface Enhancement Gradient Measured on Dual-Energy CT Images Improves Prognostic Evaluation.Radiology. Imaging cancer · 2020Article
- Intra-individual consistency of spectral detector CT-enabled iodine quantification of the vascular and renal blood pool.European radiology · 2019Article
- Effects of radiation dose levels and spectral iterative reconstruction levels on the accuracy of iodine quantification and virtual monochromatic CT numbers in dual-layer spectral detector CT: an iodine phantom study.Quantitative imaging in medicine and surgery · 2019Article
- How new technologies could impact on radiology diagnosis and assessment of pancreatic lesions: Future perspectives.Endoscopic ultrasoundArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Pancreatic cancer remains a major health problem, and only less than 20% of patients have resectable disease at the time of initial diagnosis. Systemic chemotherapy is often used in the patients with borderline resectable, locally advanced unresectable disease and metastatic disease. CT is often used to assess for therapeutic response; however, conventional imaging including CT may not correctly reflect treatment response after chemotherapy. Dual-energy (DE) CT can acquire datasets at two different photon spectra in a single CT acquisition, and permits separating materials and extract iodine by applying a material decomposition algorithm. Quantitative iodine mapping may have an added value over conventional CT imaging for monitoring the treatment effects in patients with pancreatic cancer and potentially serve as a unique biomarker for treatment response. In this pictorial essay, we will review the technique for iodine quantification of pancreatic cancer by DECT and discuss our observations of iodine quantification at baseline and after systemic chemotherapy with conventional cytotoxic agents, and illustrate example cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.