Evidence map›Paper›PMID 29473035›Full record

ReviewFrontiers in bioengineering and biotechnology2018

The Role of Noncoding RNA Pseudouridylation in Nuclear Gene Expression Events.

Yang Zhao, William Dunker, Yi-Tao Yu, John Karijolich

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Advancements in pseudouridine modifying enzyme and cancer.Frontiers in cell and developmental biology · 2024
    Review
  7. Effect of NaCl stress on exoproteome profiles ofFrontiers in microbiology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Long Non-Coding RNA Epigenetics.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. The role of mMolecular cancer · 2021
    Review
  18. Article
  19. Epitranscriptomics in Normal and Malignant Hematopoiesis.International journal of molecular sciences · 2020
    Review
  20. Naturally occurring modified ribonucleosides.Wiley interdisciplinary reviews. RNA · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yang ZhaoDepartment of Pathology, Microbiology, and Immunology, School of Medicine, Vanderbilt University, Nashville, TN, United States.
William DunkerDepartment of Pathology, Microbiology, and Immunology, School of Medicine, Vanderbilt University, Nashville, TN, United States.
Yi-Tao YuDepartment of Biochemistry and Biophysics, Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, United States.
John KarijolichDepartment of Pathology, Microbiology, and Immunology, School of Medicine, Vanderbilt University, Nashville, TN, United States.
Vanderbilt University · USUniversity of Rochester · US

Funding

Expanding the genetic code by targeted pseudouridylationR01GM104077 · NIGMS · UNIVERSITY OF ROCHESTER · PI YU, YI-TAO · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM104077
6 · The paper itself

Abstract

Pseudouridine is the most abundant internal RNA modification in stable noncoding RNAs (ncRNAs). It can be catalyzed by both RNA-dependent and RNA-independent mechanisms. Pseudouridylation impacts both the biochemical and biophysical properties of RNAs and thus influences RNA-mediated cellular processes. The investigation of nuclear-ncRNA pseudouridylation has demonstrated that it is critical for the proper control of multiple stages of gene expression regulation. Here, we review how nuclear-ncRNA pseudouridylation contributes to transcriptional regulation and pre-mRNA splicing.

Indexed as

7SK RNApre-mRNA splicingRNA pseudouridylationspliceosomal small nuclear RNAsteroid receptor RNA activatortranscription

Identifiers

PMID29473035
PMCPMC5809436
OpenAlexW2793020236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.