Evidence map›Paper›PMID 29472926›Full record

ArticleFrontiers in immunology2018

Eliminating Factor H-Binding Activity of

Ashley L Marcinkiewicz, Ilva Lieknina, Svetlana Kotelovica, Xiuli Yang, Peter Kraiczy, Utpal Pal, Yi-Pin Lin, Kaspars Tars

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Current and emerging approaches for eliminatingFrontiers in microbiology · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashley L MarcinkiewiczDivision of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, United States.
Ilva LiekninaLatvian Biomedical Research and Study Centre, Riga, Latvia.
Svetlana KotelovicaLatvian Biomedical Research and Study Centre, Riga, Latvia.
Xiuli YangDepartment of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, College Park, MD, United States.
Peter KraiczyInstitute of Medical Microbiology and Infection Control, University Hospital of Frankfurt, Frankfurt am Main, Germany.
Utpal PalDepartment of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, College Park, MD, United States.
Yi-Pin LinDivision of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, United States.
Kaspars TarsLatvian Biomedical Research and Study Centre, Riga, Latvia.

Funding

BORRELIA GENE PRODUCTS CRITICAL FOR NATURAL INFECTION CYCLER01AI080615 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL · 2009 to 2024
$5.2M
Multiple B. burgdorferi Factors Collaborate to Evade Complement-Mediated DefensesR01AI121401 · NIAID · TUFTS UNIVERSITY BOSTON · PI COBURN, JENIFER L, LEONG, JOHN M · 2016 to 2020
$3.1M
BBA57-Mediated Borrelial Persistence, Genesis of Inflammation and ImmunityR01AI116620 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL · 2015 to 2019
$1.9M
NIAID NIH HHS R01 AI080615NIAID NIH HHS R01 AI116620NIAID NIH HHS R01 AI121401
6 · The paper itself

Abstract

The spirochete

Indexed as

AnimalsAntibodies, BacterialBacterial Outer Membrane ProteinsBorrelia burgdorferiComplement Factor HImmunization, PassiveLyme DiseaseLyme Disease VaccinesMaleMiceSerum Bactericidal Antibody AssayVaccines, Virus-Like ParticleAntibodies, BacterialBacterial Outer Membrane ProteinsComplement Factor HLyme Disease VaccinesVaccines, Virus-Like ParticleBorreliaCspZfactor HLyme diseasevaccinevirus-like particles

Identifiers

PMID29472926
PMCPMC5809437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.