Evidence map›Paper›PMID 29472885›Full record

ArticleFrontiers in neurology2017

The Pathoconnectivity Profile of Alzheimer's Disease: A Morphometric Coalteration Network Analysis.

Jordi Manuello, Andrea Nani, Enrico Premi, Barbara Borroni, Tommaso Costa, Karina Tatu, Donato Liloia, Sergio Duca, Franco Cauda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  6. A co-alteration parceling of the cingulate cortex.Brain structure & function · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jordi ManuelloGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.
Andrea NaniGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.
Enrico PremiNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Barbara BorroniNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Tommaso CostaGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.
Karina TatuGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.
Donato LiloiaFOCUS Laboratory, Department of Psychology, University of Turin, Turin, Italy.
Sergio DucaGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.
Franco CaudaGCS-fMRI, Department of Psychology, Koelliker Hospital, University of Turin, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gray matter alterations are typical features of brain disorders. However, they do not impact on the brain randomly. Indeed, it has been suggested that neuropathological processes can selectively affect certain assemblies of neurons, which typically are at the center of crucial functional networks. Because of their topological centrality, these areas form a

Indexed as

Alzheimer’s diseasebrain alterationscoatrophy networkgray matter atrophypathoconnectivity hubstauopathyvoxel-based morphometry

Identifiers

PMID29472885
PMCPMC5810291

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.