ArticleFrontiers in physiology2018
High-Intensity Interval Training in Normobaric Hypoxia Leads to Greater Body Fat Loss in Overweight/Obese Women than High-Intensity Interval Training in Normoxia.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- The effects of hypoxic versus normoxic exercise training on body composition, cardiometabolic health markers, and functional performance in adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta-analysis.Diabetes, obesity & metabolism · 2026Pooled it
- Effects of exercise interventions in hypoxic environment on cardiovascular function and maximal power output in obese or overweight individuals: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Effects of Aerobic Exercise Training in Hypoxia Versus Normoxia on Body Composition and Metabolic Health in Overweight and/or Obese Populations: an Updated Meta-Analysis.Sports medicine - open · 2025Pooled it
- Impact of exercise training in a hypobaric/normobaric hypoxic environment on body composition and glycolipid metabolism in individuals with overweight or obesity: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Impact of Exercise in Hypoxia on Inflammatory Cytokines in Adults: A Systematic Review and Meta-analysis.Sports medicine - open · 2023Pooled it
- Effects of 4-week continuous hypoxic training on skeletal muscle oxygenation using near-infrared spectroscopy and functional magnetic resonance imaging.European journal of applied physiology · 2026Trial
- Repeated sprint in hypoxia as a time-metabolic efficient strategy to improve physical fitness of obese women.European journal of applied physiology · 2020Trial
- Trial
- Association Between Body Mass Index and Physical Fitness Among University Students in a Sub-Plateau Region of Gansu Province, China: A Cross-Sectional Study.Life (Basel, Switzerland) · 2026Article
- Cardiometabolic Risk Factors in Women Exposed to High Altitude.International journal of molecular sciences · 2026Review
- The Influence of Training with an Evaluation Mask on Physiological Adaptations in a Recreational Athlete.Journal of functional morphology and kinesiology · 2026Article
- Dose-response relationship of normobaric hypoxia training on body composition and metabolic health in obese adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Article
- Intermittent hypoxic conditioning as a novel strategy for obesity treatment: current evidence and future perspectives.Frontiers in physiology · 2026Review
- Effects and adaptation of high-altitude hypoxia on lipid metabolism: mechanisms and health implications.Frontiers in physiology · 2026Review
- The Impact of Exercise Training in a Hypobaric/Normobaric Hypoxic Environment on Cardiometabolic Health in Adults with Overweight or Obesity: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Normobaric hypoxia accelerates high-intensity intermittent training-induced mitochondrial biogenesis (PGC-1α)- and dynamics (OPA1)-related protein expressions in rat gastrocnemius muscle.Journal of physiology and biochemistry · 2024Article
- Mechanisms for Combined Hypoxic Conditioning and Divergent Exercise Modes to Regulate Inflammation, Body Composition, Appetite, and Blood Glucose Homeostasis in Overweight and Obese Adults: A Narrative Review.Sports medicine (Auckland, N.Z.) · 2023Review
- A framework of transient hypercapnia to achieve an increased cerebral blood flow induced by nasal breathing during aerobic exercise.Cerebral circulation - cognition and behavior · 2023Review
- Hypoxic repeated sprint interval training improves cardiorespiratory fitness in sedentary young women.Journal of exercise science and fitness · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investigate if exposure to hypoxia combined with two different protocols of high-intensity interval exercise in overweight/obese women was more effective compared with exercise in normoxia. Study participants included 82 overweight/obese women, who started a 12 week program of 36 sessions, and were randomly divided into four groups: (1) aerobic interval training in hypoxia (AitH; FiO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.