Evidence map›Paper›PMID 29472865›Full record

ArticleFrontiers in physiology2018

Intracranial Pressure Is a Determinant of Sympathetic Activity.

Eric A Schmidt, Fabien Despas, Anne Pavy-Le Traon, Zofia Czosnyka, John D Pickard, Kamal Rahmouni, Atul Pathak, Jean M Senard

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04094974 (The Usefulness of the Combination of Preoperative Assessment of Optic Nerve Sheath Diameter and Heart Rate Variability to Predict Intraoperative Brain Condition in Patients With Supratentorial Tumors), which is not on this map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04094974 completednot on this mapstarted 2019, after this paper: background citation

The Usefulness of the Combination of Preoperative Assessment of Optic Nerve Sheath Diameter and Heart Rate Variability to Predict Intraoperative Brain Condition in Patients With Supratentorial Tumors

TypeobservationalSponsorDyAnsys, Inc.Ran2019 to 2020Enrolled58ConditionsSupratentorial Brain TumorsArmsANSiscope
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
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  6. Resuscitative endovascular occlusion of the aorta restores cerebral metabolic markers of ischaemia induced by haemorrhagic shock.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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  16. Point of care ultrasound evaluation of cardio-cerebral coupling.World journal of critical care medicine · 2025
    Review
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Eric A SchmidtInstitut des Maladies Métaboliques et Cardiovasculaires, I2MC, Institut National de la Santé et de la Recherche Médicale, Université de Toulouse, Toulouse, France.
Fabien DespasInstitut des Maladies Métaboliques et Cardiovasculaires, I2MC, Institut National de la Santé et de la Recherche Médicale, Université de Toulouse, Toulouse, France.
Anne Pavy-Le TraonInstitut des Maladies Métaboliques et Cardiovasculaires, I2MC, Institut National de la Santé et de la Recherche Médicale, Université de Toulouse, Toulouse, France.
Zofia CzosnykaBrain Physics Lab, Academic Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
John D PickardBrain Physics Lab, Academic Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
Kamal RahmouniDepartments of Pharmacology, University of Iowa, Iowa City, IA, United States.
Atul PathakInstitut des Maladies Métaboliques et Cardiovasculaires, I2MC, Institut National de la Santé et de la Recherche Médicale, Université de Toulouse, Toulouse, France.
Jean M SenardInstitut des Maladies Métaboliques et Cardiovasculaires, I2MC, Institut National de la Santé et de la Recherche Médicale, Université de Toulouse, Toulouse, France.
Institut des Maladies Métaboliques et Cardiovasculaires · FRUniversité de Toulouse · FRUniversity of Cambridge · GBUniversity of Iowa · US

Funding

Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
NHLBI NIH HHS P01 HL084207
6 · The paper itself

Abstract

Intracranial pressure (ICP) is the pressure within the

Indexed as

autonomic nervous systembaroreflexintracranial pressuremicroneurographyphysiologytranslational medical research

Identifiers

PMID29472865
PMCPMC5809772
OpenAlexW2789620984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.